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In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
Revenues: |
United States | | | | | 696.8 | 588.2 | | 444.1 |
Net product revenues | | | | | | | | 884.5 |
Other | | | | | 794.4 | 725.4 | | |
Total revenues [+] | 2,096.0 | 1,846.3 | 1,860.5 | 1,704.0 | 1,491.2 | 1,313.6 | 1,116.9 | 889.9 |
Royalties | | | | | | | | 5.4 |
Products | | | | | | | | 884.5 |
Revenue growth [+] | 13.5% | -0.8% | 9.2% | 14.3% | 13.5% | 17.6% | 25.5% | 18.8% |
United States | | | | | 18.5% | | | 15.7% |
Net product revenues | | | | | | | | 19.8% |
Cost of goods sold | 483.7 | 470.5 | 524.3 | 359.5 | 315.3 | 241.8 | 209.6 | 152.0 |
Gross profit | 1,612.4 | 1,375.8 | 1,336.2 | 1,344.6 | 1,175.9 | 1,071.9 | 907.2 | 737.9 |
Gross margin | 76.9% | 74.5% | 71.8% | 78.9% | 78.9% | 81.6% | 81.2% | 82.9% |
Selling, general and administrative | 854.0 | 759.4 | 737.7 | 680.9 | 604.4 | 554.3 | 476.6 | 402.3 |
Research and development | 649.6 | 628.8 | 628.1 | 715.0 | 696.3 | 610.8 | 661.9 | 634.8 |
Equity in earnings | | | | | -0.6 | -1.3 | -0.5 | -0.8 |
Other operating expenses | 67.2 | 69.9 | 66.7 | 74.1 | 48.8 | 46.5 | -27.0 | -17.7 |
EBITDA [+] | 143.5 | 25.7 | 8.9 | -20.2 | -78.4 | -53.1 | -107.9 | -235.1 |
EBITDA growth | 458.5% | 188.4% | -144.2% | -74.3% | 47.6% | -50.8% | -54.1% | 103.8% |
EBITDA margin | 6.8% | 1.4% | 0.5% | -1.2% | -5.3% | -4.0% | -9.7% | -26.4% |
Depreciation and amortization | 102.0 | 108.0 | 105.2 | 105.3 | 95.7 | 87.9 | 96.9 | 47.2 |
EBIT [+] | 41.6 | -82.3 | -96.3 | -125.5 | -174.1 | -141.0 | -204.8 | -282.3 |
EBIT growth | -150.5% | -14.5% | -23.3% | -27.9% | 23.5% | -31.2% | -27.4% | 75.1% |
EBIT margin | 2.0% | -4.5% | -5.2% | -7.4% | -11.7% | -10.7% | -18.3% | -31.7% |
Non-recurring items [+] | -108.0 | | -52.8 | -25.0 | -50.0 | -125.0 | 599.1 | -170.8 |
Asset impairment | | | | | | | 599.1 | 198.7 |
Loss (gain) on sale of assets | -108.0 | | -52.8 | -25.0 | -50.0 | -125.0 | | -369.5 |
Interest expense, net [+] | -2.1 | 4.9 | 12.7 | 0.7 | 20.8 | 27.9 | 32.0 | 33.7 |
Interest expense | 16.0 | 15.3 | 29.3 | 23.5 | 43.7 | 42.7 | 39.5 | 38.2 |
Interest income | 18.0 | 10.5 | 16.6 | 22.7 | 22.8 | 14.9 | 7.5 | 4.5 |
Other income (expense), net | -2.1 | 11.8 | 7.1 | 6.4 | 2.2 | 8.0 | 4.9 | -9.5 |
Pre-tax income | 149.6 | -75.4 | -49.0 | -94.8 | -142.7 | -35.9 | -831.1 | -154.7 |
Income taxes | 8.0 | -11.3 | -903.0 | -71.0 | -65.5 | 81.2 | -200.8 | 17.1 |
Tax rate | 5.4% | 15.0% | 1843.0% | 74.8% | 45.9% | | 24.2% | |
Net income | 141.6 | -64.1 | 854.0 | -23.8 | -77.2 | -117.0 | -630.2 | -171.8 |
Net margin | 6.8% | -3.5% | 45.9% | -1.4% | -5.2% | -8.9% | -56.4% | -19.3% |
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Basic EPS [+] | $0.76 | ($0.35) | $4.72 | ($0.13) | ($0.44) | ($0.67) | ($3.80) | ($1.07) |
Growth | -318.0% | -107.4% | -3646.2% | -69.5% | -35.0% | -82.3% | 253.7% | 17.3% |
Diluted EPS [+] | $0.75 | ($0.35) | $4.46 | ($0.13) | ($0.44) | ($0.67) | ($3.79) | ($1.07) |
Growth | -313.8% | -107.9% | -3445.0% | -69.4% | -35.1% | -82.3% | 253.2% | 17.3% |
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Shares outstanding (basic) [+] | 185.3 | 182.9 | 180.8 | 179.0 | 177.1 | 174.4 | 166.0 | 160.0 |
Growth | 1.3% | 1.1% | 1.0% | 1.1% | 1.5% | 5.1% | 3.7% | 9.3% |
Shares outstanding (diluted) [+] | 189.0 | 182.9 | 191.7 | 179.0 | 177.3 | 174.4 | 166.2 | 160.0 |
Growth | 3.3% | -4.6% | 7.1% | 1.0% | 1.6% | 4.9% | 3.9% | 9.3% |
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EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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