| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 |
| | 20-F | 20-F | 20-F |
| Revenues: |
| Reimbursements | 1.9 | 0.4 | 2.8 |
| License Fees | 3.5 | 11.0 | 2.3 |
| Research And Development Services | 2.1 | 2.2 | 1.7 |
| Other | | | 3.5 |
| Total revenues | 7.5 | 13.7 | 10.3 |
| Revenue growth [+] | -45.5% | 32.6% | |
| Reimbursements | 312.9% | -83.9% | |
| License Fees | -67.9% | 381.5% | |
| Research And Development Services | -7.1% | 27.8% | |
| Cost of goods sold | 0.0 | 0.0 | 0.0 |
| Gross profit | 7.5 | 13.7 | 10.3 |
| Gross margin | 100.0% | 100.0% | 100.0% |
| Selling, general and administrative [+] | 17.1 | 6.4 | 6.4 |
| General and administrative | 17.1 | 6.4 | 6.4 |
| Research and development | 54.8 | 20.4 | 26.4 |
| Other operating expenses | 0.0 | 0.0 | 0.0 |
| EBITDA [+] | -62.3 | -11.2 | -20.4 |
| EBITDA growth | 457.4% | -45.3% | |
| EBITDA margin | -835.3% | -81.7% | -198.0% |
| Depreciation | 0.6 | 0.5 | 0.6 |
| EBITA | -62.8 | -11.7 | -21.0 |
| EBITA margin | -842.7% | -85.3% | -203.9% |
| Amortization of intangibles | 1.6 | 1.5 | 1.5 |
| EBIT [+] | -64.4 | -13.1 | -22.5 |
| EBIT growth | 391.2% | -41.6% | |
| EBIT margin | -864.2% | -95.9% | -217.9% |
| Interest income | | 0.0 | 0.2 |
| Interest income | | 0.0 | 0.2 |
| Other income (expense), net | -3.9 | -4.8 | 0.0 |
| Pre-tax income | -68.3 | -17.8 | -22.3 |
| Income taxes | 0.0 | 0.0 | 0.0 |
| Tax rate | | | 0.0% |
| Net income | -68.3 | -17.8 | -22.3 |
| Net margin | -916.0% | -130.5% | -216.4% |
| |
| Basic EPS [+] | ($0.48) | ($0.15) | ($0.16) |
| Growth | 209.3% | -5.9% | |
| Diluted EPS [+] | ($0.48) | ($0.15) | ($0.16) |
| Growth | 209.3% | -5.9% | |
| |
| Shares outstanding (basic) [+] | 143.2 | 115.7 | 136.1 |
| Growth | 23.8% | -15.0% | |
| Shares outstanding (diluted) [+] | 143.2 | 115.7 | 136.1 |
| Growth | 23.8% | -15.0% | |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |