| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 7.8k | $7.00 | $54.5k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 4k | $22.70 | $90.8k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 4k | $7.60 | $30.4k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 4k | $7.52 | $30.1k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 12.5k | $7.27 | $90.9k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 22.5k | $4.27 | $96.1k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 1.2k | $25.90 | $32.4k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 1.2k | $15.70 | $19.6k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 2.5k | $16.10 | $40.5k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 2k | $20.00 | $40k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Stock Option (Right to Buy) | 6.4k | $9.20 | $58.9k | | 01/19/2023 |
| 01/19/2023 | AVEO PHARMACEUTICALS, INC. | AVEO | Disposition | Common Stock | 375 | $15.00 | $5.6k | | 01/19/2023 |
| 08/12/2022 | Epizyme, Inc. | EPZM | Disposition | Common Stock, par value $0.0001 | 8.1k | $0.00 | $0 | | 08/12/2022 |
| 08/12/2022 | Epizyme, Inc. | EPZM | Disposition | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 08/12/2022 |
| 06/16/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 9.5k | $65.06 | $616.1k | | 06/16/2022 |
| 06/09/2022 | Astria Therapeutics, Inc. | ATXS | Grant | Stock Option (right to buy) | 8.3k | $0.00 | $0 | | 06/09/2022 |
| 06/09/2022 | Astria Therapeutics, Inc. | ATXS | Grant | Stock Option (right to buy) | 8.3k | $2.99 | $24.9k | | 06/09/2022 |
| 06/07/2022 | AVEO PHARMACEUTICALS, INC. | AVEO | Grant | Stock Option (right to buy) | 22.5k | $4.27 | $96.1k | | 06/07/2022 |
| 05/17/2022 | Epizyme, Inc. | EPZM | Grant | Stock Option (Right to Buy) | 41k | $0.56 | $23k | | 05/17/2022 |
| 05/17/2022 | Epizyme, Inc. | EPZM | Grant | Common Stock, par value $0.0001 | 9k | $0.00 | $0 | | 05/17/2022 |
| 06/17/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 12.5k | $105.08 | $1.3M | | 06/17/2021 |
| 06/11/2021 | Epizyme, Inc. | EPZM | Grant | Common Stock, par value $0.0001 | 8.1k | $0.00 | $0 | | 06/11/2021 |
| 06/11/2021 | Epizyme, Inc. | EPZM | Grant | Stock Option (Right to Buy) | 40.6k | $8.53 | $346k | | 06/11/2021 |
| 06/09/2021 | AVEO PHARMACEUTICALS, INC. | AVEO | Grant | Stock Option (right to buy) | 12.5k | $7.27 | $90.9k | | 06/09/2021 |
| 06/02/2021 | Astria Therapeutics, Inc. | ATXS | Grant | Stock Option (right to buy) | 100k | $2.04 | $204k | | 06/02/2021 |
| 06/18/2020 | GENOCEA BIOSCIENCES, INC. | GNCA | Grant | Stock Option (Right to Buy) | 15k | $2.22 | $33.3k | | 06/18/2020 |
| 06/17/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 6k | $111.06 | $666.4k | | 06/17/2020 |
| 06/11/2020 | Astria Therapeutics, Inc. | ATXS | Grant | Stock Option (right to buy) | 7.5k | $6.17 | $46.3k | | 06/11/2020 |
| 06/10/2020 | AVEO PHARMACEUTICALS, INC. | AVEO | Grant | Stock Option (right to buy) | 4k | $7.52 | $30.1k | | 06/10/2020 |
| 05/29/2020 | Epizyme, Inc. | EPZM | Grant | Stock Option (Right to Buy) | 14k | $17.55 | $245.9k | | 05/29/2020 |
| 07/18/2019 | GENOCEA BIOSCIENCES, INC. | GNCA | Grant | Stock Option (Right to Buy) | 5.6k | $3.66 | $20.6k | | 07/18/2019 |
| 06/27/2019 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 10k | $100.45 | $1M | | 06/27/2019 |
| 06/12/2019 | AVEO PHARMACEUTICALS, INC. | AVEO | Grant | Stock Option (right to buy) | 40k | $0.76 | $30.4k | | 06/12/2019 |
| 06/04/2019 | Astria Therapeutics, Inc. | ATXS | Grant | Stock Option (right to buy) | 7.5k | $6.53 | $49k | | 06/04/2019 |
| 05/31/2019 | Epizyme, Inc. | EPZM | Grant | Stock Option (Right to Buy) | 17.6k | $13.74 | $242.3k | | 05/31/2019 |
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