| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/17/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | Grant | Stock Option (Right to Buy) | 15k | $76.00 | $1.1M | | 05/17/2023 |
| 08/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | Grant | Stock Option (Right to Buy) | 30k | $27.57 | $827.1k | | 08/31/2022 |
| 08/27/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 701 | $30.76 | $21.6k | | 08/26/2021 |
| 08/27/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 250 | $31.44 | $7.9k | | 08/26/2021 |
| 08/26/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 13.5k | $30.12 | $406.8k | | 08/26/2021 |
| 08/26/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 558 | $31.01 | $17.3k | | 08/26/2021 |
| 08/25/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 9.5k | $30.08 | $285.1k | | 08/24/2021 |
| 08/24/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 505 | $30.03 | $15.2k | | 08/24/2021 |
| 08/24/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 3 | $30.04 | $90.1 | | 08/24/2021 |
| 07/02/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 198.8k | $43.30 | $8.6M | | 07/02/2021 |
| 07/02/2021 | Applied Molecular Transport Inc. | AMTI | Sale | Common Stock | 1.2k | $46.31 | $57.5k | | 07/02/2021 |
| 05/18/2021 | Applied Molecular Transport Inc. | AMTI | Grant | Stock Option (Right to Buy) | 14.3k | $47.01 | $674.3k | | 05/18/2021 |
| 07/02/2020 | Applied Molecular Transport Inc. | AMTI | Exercise | Stock Option (Right to Buy) | 800k | $0.02 | $16k | | 07/02/2020 |
| 06/11/2020 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 10k | $20.47 | $204.7k | | 06/11/2020 |
| 06/04/2020 | EXICURE, INC. | XCUR | Grant | Stock Option (right to buy) | 21.7k | $2.79 | $60.5k | | 06/04/2020 |
| 06/14/2019 | EXICURE, INC. | XCUR | Grant | Stock Option (right to buy) | 21.7k | $2.78 | $60.3k | | 06/14/2019 |
| 05/17/2019 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 10k | $15.22 | $152.2k | | 05/17/2019 |
| 06/19/2018 | EXICURE, INC. | XCUR | Grant | Stock Option (right to buy) | 21.7k | $5.82 | $126.3k | | 06/19/2018 |
| 05/30/2018 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 7.5k | $42.09 | $315.7k | | 05/30/2018 |
| 03/08/2018 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 20k | $57.53 | $1.2M | | 03/08/2018 |
| 09/26/2017 | EXICURE, INC. | XCUR | Grant | Stock Option (right to buy) | 49.6k | $0.00 | $0 | | 09/26/2017 |
| 09/26/2017 | EXICURE, INC. | XCUR | Grant | Stock Option (right to buy) | 24.8k | $0.00 | $0 | | 09/26/2017 |
| 09/25/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 3.2k | $179.66 | $569.7k | | 09/25/2017 |
| 09/25/2017 | Kite Pharma, Inc. | KITE | Grant | Common Stock | 6k | $0.00 | $0 | | 09/25/2017 |
| 08/10/2017 | Kite Pharma, Inc. | KITE | Exercise | Employee Stock Option (Right to Buy) | 2.7k | $51.43 | $136.6k | | 08/10/2017 |
| 08/10/2017 | Kite Pharma, Inc. | KITE | Exercise | Employee Stock Option (Right to Buy) | 3.6k | $53.90 | $193.8k | | 08/10/2017 |
| 08/10/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 6.3k | $120.09 | $750.7k | | 08/10/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Exercise | Employee Stock Option (Right to Buy) | 79.9k | $53.90 | $4.3M | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 3.8k | $118.61 | $450.7k | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 1.7k | $117.27 | $199.4k | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 11.1k | $115.02 | $1.3M | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 13.3k | $121.37 | $1.6M | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 31.2k | $120.40 | $3.8M | | 08/08/2017 |
| 08/08/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 18.9k | $119.94 | $2.3M | | 08/08/2017 |
| 07/31/2017 | Kite Pharma, Inc. | KITE | Sale | Common Stock | 15.8k | $108.75 | $1.7M | | 07/31/2017 |
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