| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 03/16/2023 | Decibel Therapeutics, Inc. | DBTX | Grant | Common Stock | 195k | $0.00 | $0 | | 03/16/2023 |
| 03/16/2023 | Decibel Therapeutics, Inc. | DBTX | Grant | Stock Options (right to buy) | 72k | $3.73 | $268.6k | | 03/16/2023 |
| 02/25/2022 | Decibel Therapeutics, Inc. | DBTX | Grant | Stock Options (right to buy) | 187.5k | $3.50 | $656.2k | | 02/25/2022 |
| 09/15/2021 | Decibel Therapeutics, Inc. | DBTX | Purchase | Common Stock | 10k | $7.64 | $76.4k | | 09/15/2021 |
| 12/31/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 17k | $15.99 | $271.8k | | 12/31/2014 |
| 12/31/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 2.8k | $97.00 | $271.8k | | 12/31/2014 |
| 12/12/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Performance Based Stock Option (right to buy) | 6.7k | $63.00 | $420k | | 12/12/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 3.6k | $15.99 | $58.2k | | 11/18/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 4.5k | $91.08 | $408.5k | | 11/18/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 5.4k | $90.30 | $488.8k | | 11/18/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 3.9k | $9.14 | $35.3k | | 11/18/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 2.5k | $7.10 | $17.8k | | 11/18/2014 |
| 11/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 102 | $91.79 | $9.4k | | 11/18/2014 |
| 08/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 11k | $9.14 | $100.5k | | 08/18/2014 |
| 08/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 2.5k | $7.10 | $17.8k | | 08/18/2014 |
| 08/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 7k | $67.80 | $474.6k | | 08/18/2014 |
| 08/18/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 6.5k | $66.83 | $434.4k | | 08/18/2014 |
| 05/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 11k | $9.14 | $100.5k | | 05/19/2014 |
| 05/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 2.5k | $7.10 | $17.8k | | 05/19/2014 |
| 05/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 10.9k | $58.01 | $632.3k | | 05/19/2014 |
| 05/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 2.6k | $57.07 | $148.4k | | 05/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 3.5k | $15.99 | $56k | | 02/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 10k | $7.10 | $71k | | 02/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 400 | $81.45 | $32.6k | | 02/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 5.5k | $80.85 | $441.1k | | 02/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 11.5k | $80.02 | $917.5k | | 02/19/2014 |
| 02/19/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 3.1k | $78.62 | $242.1k | | 02/19/2014 |
| 01/23/2014 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 3.7k | $89.49 | $330.9k | | 01/23/2014 |
| 12/30/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 930 | $64.51 | $60k | | 12/30/2013 |
| 12/30/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 3.8k | $15.99 | $60k | | 12/30/2013 |
| 12/18/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 20k | $63.00 | $1.3M | | 12/18/2013 |
| 11/13/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 13.5k | $53.36 | $720.3k | | 11/13/2013 |
| 11/13/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 13.5k | $15.99 | $215.9k | | 11/13/2013 |
| 05/28/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 5k | $30.00 | $150k | | 05/28/2013 |
| 05/28/2013 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (Right to Buy) | 5k | $7.10 | $35.5k | | 05/28/2013 |
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