| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/07/2023 | Vigil Neuroscience, Inc. | | Grant | Stock Option Grant (Right to Buy) | 13.9k | $10.00 | $139.3k | | 06/07/2023 |
| 06/07/2023 | PLIANT THERAPEUTICS, INC. | PLRX | Grant | Stock Option (Right to Buy) | 14k | $23.09 | $323.3k | | 06/07/2023 |
| 05/17/2023 | Travere Therapeutics, Inc. | RTRX | Grant | | 13.5k | $17.11 | $231k | | 05/17/2023 |
| 05/17/2023 | Travere Therapeutics, Inc. | RTRX | Grant | | 4.5k | $0.00 | $0 | | 05/17/2023 |
| 08/11/2022 | Mind Medicine (MindMed) Inc. | | Grant | Director's Deferred Share Units | 503.8k | $0.00 | $0 | | 08/11/2022 |
| 08/11/2022 | Mind Medicine (MindMed) Inc. | | Grant | Stock Option (Right to Buy) | 121k | $0.00 | $0 | | 08/11/2022 |
| 08/11/2022 | Mind Medicine (MindMed) Inc. | | Grant | Common Shares | 89.3k | $0.00 | $0 | | 08/11/2022 |
| 07/27/2022 | Vigil Neuroscience, Inc. | | Grant | Stock Option Grant (Right to Buy) | 24.3k | $6.93 | $168.5k | | 07/27/2022 |
| 06/16/2022 | PLIANT THERAPEUTICS, INC. | PLRX | Grant | Stock Option (right to buy) | 15k | $6.80 | $102k | | 06/16/2022 |
| 05/11/2022 | Travere Therapeutics, Inc. | RTRX | Grant | | 9k | $21.38 | $192.4k | | 05/11/2022 |
| 05/11/2022 | Travere Therapeutics, Inc. | RTRX | Grant | | 3k | $0.00 | $0 | | 05/11/2022 |
| 09/30/2021 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 5.2k | $2.18 | $11.3k | | 09/30/2021 |
| 06/30/2021 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 3.5k | $3.27 | $11.3k | | 06/30/2021 |
| 06/29/2021 | PLIANT THERAPEUTICS, INC. | PLRX | Grant | Stock Option (right to buy) | 13.3k | $28.20 | $374.7k | | 06/29/2021 |
| 06/15/2021 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 40k | $3.56 | $142.4k | | 06/15/2021 |
| 05/14/2021 | Travere Therapeutics, Inc. | RTRX | Grant | | 3k | $0.00 | $0 | | 05/14/2021 |
| 05/14/2021 | Travere Therapeutics, Inc. | RTRX | Grant | | 9k | $18.27 | $164.4k | | 05/14/2021 |
| 03/31/2021 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 4.2k | $3.02 | $12.6k | | 03/31/2021 |
| 12/31/2020 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 4.3k | $2.64 | $11.2k | | 12/31/2020 |
| 09/30/2020 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 4.3k | $2.28 | $9.8k | | 09/30/2020 |
| 06/30/2020 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 2.1k | $2.60 | $5.5k | | 06/30/2020 |
| 06/18/2020 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 25k | $2.51 | $62.8k | | 06/18/2020 |
| 06/08/2020 | Aeglea BioTherapeutics, Inc. | AGLE | Grant | Director Stock Option (right to buy) | 28.1k | $8.89 | $249.8k | | 06/08/2020 |
| 04/24/2020 | Avalo Therapeutics, Inc. | CERC | Grant | Stock Option (Right to Buy) | 50k | $2.58 | $129k | | 04/24/2020 |
| 04/08/2020 | Travere Therapeutics, Inc. | RTRX | Grant | Stock Option (Right to Buy) | 15.8k | $15.63 | $246.2k | | 04/08/2020 |
| 04/08/2020 | Travere Therapeutics, Inc. | RTRX | Grant | Common Stock | 5.2k | $0.00 | $0 | | 04/08/2020 |
| 06/07/2019 | Aeglea BioTherapeutics, Inc. | AGLE | Grant | Director Stock Option (right to buy) | 12.4k | $6.33 | $78.5k | | 06/07/2019 |
| 08/09/2018 | NOVELION THERAPEUTICS INC. | NVLNF | Grant | Stock Option (Right to Buy) | 10k | $0.00 | $0 | | 08/09/2018 |
| 06/07/2018 | Aeglea BioTherapeutics, Inc. | AGLE | Grant | Director Stock Option (right to buy) | 18.4k | $10.28 | $189.2k | | 06/07/2018 |
| 02/15/2017 | Aeglea BioTherapeutics, Inc. | AGLE | Grant | Director Stock Option (right to buy) | 82k | $5.04 | $413.3k | | 02/15/2017 |
| 10/25/2016 | HORIZON PHARMACEUTICAL LLC | RPTP | Disposition | Common Stock | 8.3k | $9.00 | $75k | | 10/24/2016 |
| 10/25/2016 | HORIZON PHARMACEUTICAL LLC | RPTP | Disposition | Stock Option (right to buy) | 90k | $5.13 | $461.7k | | 10/24/2016 |
| 10/25/2016 | HORIZON PHARMACEUTICAL LLC | RPTP | Disposition | Stock Option (right to buy) | 30.7k | $5.49 | $168.4k | | 10/24/2016 |
| 10/24/2016 | HORIZON PHARMACEUTICAL LLC | RPTP | Other | Common Stock | 48.4k | $9.00 | $435.9k | | 10/24/2016 |
| 03/13/2014 | HORIZON PHARMACEUTICAL LLC | RPTP | Sale | Common Stock | 2.8k | $15.21 | $42k | | 03/13/2014 |
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