| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/28/2018 | STRYKER CORP | 10% Owner | Other (acquisition) | Stock Option (right to buy) | 4M | $0.00 | $0 | | 02/28/2018 |
| 02/28/2018 | STRYKER CORP | 10% Owner | Other (acquisition) | Common Stock, $0.001 par value per share | 26M | $0.00 | $0 | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Common Stock, $0.001 par value | 291.7k | $24.00 | $7M | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 39.6k | $1.36 | $53.8k | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 28.4k | $0.76 | $21.6k | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 34.5k | $1.24 | $42.8k | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 188.8k | $11.36 | $2.1M | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 10k | $18.26 | $182.6k | | 02/28/2018 |
| 02/28/2018 | Farley Brian E | Director | Disposition | Stock Option (right to buy) | 5k | $13.38 | $66.9k | | 02/28/2018 |
| 02/28/2018 | BAKEWELL JOHN K | Director | Disposition | Common Stock, $0.001 par value | 2.5k | $24.00 | $60k | | 02/28/2018 |
| 02/28/2018 | BAKEWELL JOHN K | Director | Disposition | Stock Option (right to buy) | 10k | $18.26 | $182.6k | | 02/28/2018 |
| 02/28/2018 | BAKEWELL JOHN K | Director | Disposition | Stock Option (right to buy) | 5k | $13.38 | $66.9k | | 02/28/2018 |
| 02/28/2018 | NEELS GUIDO J | Director | Disposition | Common Stock, $0.001 par value | 17.5k | $24.00 | $420k | | 02/28/2018 |
| 02/28/2018 | NEELS GUIDO J | Director | Disposition | Stock Option (right to buy) | 15k | $11.36 | $170.4k | | 02/28/2018 |
| 02/28/2018 | NEELS GUIDO J | Director | Disposition | Stock Option (right to buy) | 10k | $18.26 | $182.6k | | 02/28/2018 |
| 02/28/2018 | NEELS GUIDO J | Director | Disposition | Stock Option (right to buy) | 5k | $13.38 | $66.9k | | 02/28/2018 |
| 02/28/2018 | MOMTAZEE JAMES C | Director | Disposition | Common Stock, $0.001 par value | 3.8k | $24.00 | $90k | | 02/28/2018 |
| 02/28/2018 | MOMTAZEE JAMES C | Director | Disposition | Stock Option (right to buy) | 7.5k | $17.67 | $132.5k | | 02/28/2018 |
| 02/28/2018 | McCormick Shawn | Director | Disposition | Stock Option (right to buy) | 15k | $11.36 | $170.4k | | 02/28/2018 |
| 02/28/2018 | McCormick Shawn | Director | Disposition | Stock Option (right to buy) | 10k | $18.26 | $182.6k | | 02/28/2018 |
| 02/28/2018 | McCormick Shawn | Director | Disposition | Stock Option (right to buy) | 5k | $13.38 | $66.9k | | 02/28/2018 |
| 02/28/2018 | McCormick Shawn | Director | Disposition | Common Stock, $0.001 par value | 5.4k | $24.00 | $130.6k | | 02/28/2018 |
| 02/28/2018 | WHITE ROBERT S. | President and CEO | Disposition | Common Stock, $0.001 par value | 53.2k | $24.00 | $1.3M | | 02/28/2018 |
| 02/28/2018 | WHITE ROBERT S. | President and CEO | Disposition | Stock Option (right to buy) | 463.3k | $11.36 | $5.3M | | 02/28/2018 |
| 02/28/2018 | WHITE ROBERT S. | President and CEO | Disposition | Stock Option (right to buy) | 270.3k | $11.36 | $3.1M | | 02/28/2018 |
| 02/28/2018 | WHITE ROBERT S. | President and CEO | Disposition | Stock Option (right to buy) | 135k | $16.99 | $2.3M | | 02/28/2018 |
| 02/28/2018 | WHITE ROBERT S. | President and CEO | Disposition | Stock Option (right to buy) | 76k | $19.01 | $1.4M | | 02/28/2018 |
| 02/28/2018 | Milne David Bruce | Director | Disposition | Common Stock, $0.001 par value | 2.5k | $24.00 | $60k | | 02/28/2018 |
| 02/28/2018 | Milne David Bruce | Director | Disposition | Stock Option (right to buy) | 15k | $11.36 | $170.4k | | 02/28/2018 |
| 02/28/2018 | Milne David Bruce | Director | Disposition | Stock Option (right to buy) | 10k | $18.26 | $182.6k | | 02/28/2018 |
| 02/28/2018 | Milne David Bruce | Director | Disposition | Stock Option (right to buy) | 5k | $13.38 | $66.9k | | 02/28/2018 |
| 02/28/2018 | Moen Brent | CFO and Secretary | Disposition | Common Stock, $0.001 par value | 12.9k | $24.00 | $308.8k | | 02/28/2018 |
| 02/28/2018 | Moen Brent | CFO and Secretary | Disposition | Stock Option (right to buy) | 100k | $17.74 | $1.8M | | 02/28/2018 |
| 02/28/2018 | Moen Brent | CFO and Secretary | Disposition | Stock Option (right to buy) | 15k | $19.01 | $285.2k | | 02/28/2018 |
| 02/28/2018 | Baltzell Joshua J | Director | Disposition | Common Stock, $0.001 par value | 5.4k | $24.00 | $128.4k | | 02/28/2018 |
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