| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/14/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 34.7k | $1.01 | $35k | | 06/14/2022 |
| 06/14/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 23.1k | $0.00 | $0 | | 06/14/2022 |
| 06/14/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 40 | $1.01 | $40.4 | | 06/14/2022 |
| 08/03/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 7.5k | $4.44 | $33.3k | | 08/03/2021 |
| 08/03/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 5k | $0.00 | $0 | | 08/03/2021 |
| 06/10/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 15k | $5.21 | $78.2k | | 06/10/2020 |
| 06/11/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 15k | $13.50 | $202.5k | | 06/11/2019 |
| 10/01/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 1.3k | $7.86 | $10.5k | | 10/01/2018 |
| 07/02/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 1.1k | $9.70 | $10.7k | | 07/02/2018 |
| 06/08/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Sale | Common Stock | 42.9k | $96.09 | $4.1M | | 06/08/2018 |
| 06/08/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Exercise | Stock Options (Right to Buy) | 75.7k | $21.34 | $1.6M | | 06/08/2018 |
| 06/06/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 15k | $11.30 | $169.5k | | 06/06/2018 |
| 05/09/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Exercise | Stock Options (Right to Buy) | 52k | $16.05 | $834.3k | | 05/09/2018 |
| 05/09/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Sale | Common Stock | 52k | $87.14 | $4.5M | | 05/09/2018 |
| 04/02/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 1.3k | $7.98 | $10.7k | | 04/02/2018 |
| 02/20/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Grant | Stock Options (Right to buy) | 17.5k | $89.64 | $1.6M | | 02/22/2018 |
| 02/13/2018 | WEST PHARMACEUTICAL SERVICES INC | WST | Grant | Common Stock | 4.5k | $93.00 | $420.9k | | 02/13/2018 |
| 01/02/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 754 | $13.00 | $9.8k | | 01/02/2018 |
| 12/08/2017 | WEST PHARMACEUTICAL SERVICES INC | WST | Sale | Common Stock | 21k | $99.01 | $2.1M | | 12/08/2017 |
| 10/02/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 1.7k | $8.69 | $14.9k | | 10/02/2017 |
| 07/03/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 882 | $16.90 | $14.9k | | 07/03/2017 |
| 06/07/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 15k | $18.77 | $281.6k | | 06/07/2017 |
| 04/03/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 734 | $20.32 | $14.9k | | 04/03/2017 |
| 02/14/2017 | WEST PHARMACEUTICAL SERVICES INC | WST | Grant | Common Stock | 4.6k | $86.93 | $401.9k | | 02/14/2017 |
| 05/25/2016 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 15k | $7.90 | $118.5k | | 05/25/2016 |
| 09/30/2013 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 4.8k | $2.41 | $11.6k | | 09/30/2013 |
| 08/30/2013 | WEST PHARMACEUTICAL SERVICES INC | WST | Gift | Common Stock | 3k | $0.00 | $0 | | 08/30/2013 |
| 06/05/2013 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 13.5k | $2.99 | $40.4k | | 06/05/2013 |
| 04/24/2013 | NUPATHE INC. | PATH | Grant | | 13.5k | $0.00 | $0 | | 04/24/2013 |
| 12/31/2012 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 2.9k | $3.38 | $9.9k | | 12/31/2012 |
| 09/30/2012 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 2.8k | $3.56 | $9.9k | | 09/30/2012 |
| 06/30/2012 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 2.4k | $4.03 | $9.8k | | 06/30/2012 |
| 06/07/2012 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 6.8k | $3.37 | $22.7k | | 06/07/2012 |
| 03/31/2012 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 2.8k | $3.70 | $10.4k | | 03/31/2012 |
| 06/08/2011 | NUPATHE INC. | PATH | Grant | Stock Option (Right to Buy) | 6.8k | $7.66 | $51.7k | | 06/08/2011 |
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