| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/11/2023 | Sigilon Therapeutics, Inc. | | Disposition | Common Stock | 12.2k | $0.00 | $0 | | 08/11/2023 |
| 08/11/2023 | Sigilon Therapeutics, Inc. | | Disposition | Stock Option (Right to Buy) | 35.4k | $0.75 | $26.5k | | 08/11/2023 |
| 06/08/2023 | Crinetics Pharmaceuticals, Inc. | CRNX | Purchase | Common Stock | 5k | $22.06 | $110.3k | | 06/08/2023 |
| 02/28/2023 | Sigilon Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 460k | $1.09 | $501.4k | | 02/28/2023 |
| 06/17/2022 | Crinetics Pharmaceuticals, Inc. | CRNX | Grant | Stock Option (right to buy) | 8.8k | $18.29 | $160k | | 06/17/2022 |
| 02/18/2022 | Sigilon Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 230k | $1.48 | $340.4k | | 02/18/2022 |
| 01/03/2022 | Crinetics Pharmaceuticals, Inc. | CRNX | Grant | Stock Option (right to buy) | 25k | $28.31 | $707.8k | | 01/03/2022 |
| 01/03/2022 | Crinetics Pharmaceuticals, Inc. | CRNX | Grant | Stock Option (right to buy) | 35k | $28.31 | $990.8k | | 01/03/2022 |
| 01/03/2022 | Sigilon Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 400k | $3.03 | $1.2M | | 01/03/2022 |
| 11/04/2021 | Sigilon Therapeutics, Inc. | | Grant | Common Stock | 50k | $0.00 | $0 | | 11/04/2021 |
| 02/11/2021 | Sigilon Therapeutics, Inc. | | Grant | Stock Option (Right to Buy) | 200k | $39.81 | $8M | | 02/11/2021 |
| 12/08/2020 | Sigilon Therapeutics, Inc. | | Conversion | Common Stock | 22.2k | $0.00 | $0 | | 12/08/2020 |
| 12/08/2020 | Sigilon Therapeutics, Inc. | | Conversion | Series B Convertible Preferred Stock | 22.2k | $0.00 | $0 | | 12/08/2020 |
| 03/08/2018 | Bioverativ Inc. | BIVV | Disposition | Non-Qualified Stock Option | 56.6k | $44.51 | $2.5M | | 03/08/2018 |
| 03/08/2018 | Bioverativ Inc. | BIVV | Disposition | Non-Qualified Stock Option | 113.2k | $44.51 | $5M | | 03/08/2018 |
| 03/08/2018 | Bioverativ Inc. | BIVV | Disposition | Restricted Stock Units | 42.7k | $0.00 | $0 | | 03/08/2018 |
| 03/08/2018 | Bioverativ Inc. | BIVV | Disposition | Restricted Stock Units | 14.2k | $0.00 | $0 | | 03/08/2018 |
| 03/08/2018 | Bioverativ Inc. | BIVV | Disposition | Common Stock | 5.8k | $0.00 | $0 | | 03/08/2018 |
| 02/14/2018 | Bioverativ Inc. | BIVV | Payment of Exercise | Common Stock | 2.1k | $103.52 | $220.1k | | 02/14/2018 |
| 02/14/2018 | Bioverativ Inc. | BIVV | Exercise | Restricted Stock Units | 7.1k | $0.00 | $0 | | 02/14/2018 |
| 01/31/2018 | Bioverativ Inc. | BIVV | Grant | Restricted Stock Units | 42.7k | $0.00 | $0 | | 01/31/2018 |
| 02/14/2017 | Bioverativ Inc. | BIVV | Grant | Non-Qualified Stock Option | 113.2k | $44.51 | $5M | | 02/14/2017 |
| 02/14/2017 | Bioverativ Inc. | BIVV | Grant | Non-Qualified Stock Option | 56.6k | $44.51 | $2.5M | | 02/14/2017 |
| 02/14/2017 | Bioverativ Inc. | BIVV | Grant | Restricted Stock Units | 21.3k | $0.00 | $0 | | 02/14/2017 |
| 02/14/2017 | Bioverativ Inc. | BIVV | Grant | Non-Qualified Stock Option | 56.5k | $44.51 | $2.5M | | 02/14/2017 |
| 02/14/2017 | Bioverativ Inc. | BIVV | Grant | Non-Qualified Stock Option | 113k | $44.51 | $5M | | 02/14/2017 |
| 04/21/2016 | Spark Therapeutics, Inc. | ONCE | Sale | Common Stock | 1.2k | $40.02 | $48k | | 04/20/2016 |
| 04/21/2016 | Spark Therapeutics, Inc. | ONCE | Exercise | Stock Option (right to buy) | 1000 | $3.45 | $3.4k | | 04/20/2016 |
| 04/21/2016 | Spark Therapeutics, Inc. | ONCE | Exercise | Stock Option (right to buy) | 200 | $7.50 | $1.5k | | 04/20/2016 |
| 04/20/2016 | Spark Therapeutics, Inc. | ONCE | Exercise | Stock Option (right to buy) | 1000 | $3.45 | $3.4k | | 04/20/2016 |
| 04/20/2016 | Spark Therapeutics, Inc. | ONCE | Exercise | Stock Option (right to buy) | 4.8k | $7.50 | $36k | | 04/20/2016 |
| 04/20/2016 | Spark Therapeutics, Inc. | ONCE | Sale | Common Stock | 5.8k | $40.02 | $232.1k | | 04/20/2016 |