| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 07/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 6.8k | $10.03 | $68k | | 07/03/2023 |
| 07/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 300 | $91.10 | $27.3k | | 07/03/2023 |
| 07/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 3.3k | $90.42 | $297.2k | | 07/03/2023 |
| 07/03/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 3.2k | $89.41 | $285.4k | | 07/03/2023 |
| 06/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 69.8k | $10.03 | $699.9k | | 06/05/2023 |
| 06/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 30.5k | $89.83 | $2.7M | | 06/05/2023 |
| 06/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 7.1k | $88.36 | $624.2k | | 06/05/2023 |
| 06/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 30.6k | $87.79 | $2.7M | | 06/05/2023 |
| 06/05/2023 | Apellis Pharmaceuticals, Inc. | APLS | Sale | Common Stock | 1.6k | $90.60 | $145k | | 06/05/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 11.7k | $0.00 | $0 | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 974 | $58.50 | $57k | | 02/21/2023 |
| 02/21/2023 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 16.6k | $35.46 | $587.6k | | 02/21/2023 |
| 02/10/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 975 | $51.21 | $49.9k | | 02/10/2023 |
| 01/27/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 551 | $52.77 | $29.1k | | 01/27/2023 |
| 01/20/2023 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 2.4k | $52.05 | $123.8k | | 01/20/2023 |
| 01/28/2022 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 650 | $38.59 | $25.1k | | 01/28/2022 |
| 01/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 30.8k | $0.00 | $0 | | 01/21/2022 |
| 01/21/2022 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 43.7k | $35.46 | $1.5M | | 01/21/2022 |
| 06/08/2021 | Apellis Pharmaceuticals, Inc. | APLS | Exercise | Stock Option (Right to Buy) | 39.9k | $10.03 | $400k | | 06/08/2021 |
| 02/10/2021 | Apellis Pharmaceuticals, Inc. | APLS | Payment of Exercise | Common Stock | 858 | $47.72 | $40.9k | | 02/10/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 7.5k | $0.00 | $0 | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 3.8k | $0.00 | $0 | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 45k | $44.90 | $2M | | 01/28/2021 |
| 01/28/2021 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (Right to Buy) | 22.5k | $44.90 | $1M | | 01/28/2021 |
| 02/10/2020 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock option (right to buy) | 70.1k | $44.33 | $3.1M | | 02/10/2020 |
| 02/10/2020 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Common Stock | 11.7k | $0.00 | $0 | | 02/10/2020 |
| 08/29/2019 | Apellis Pharmaceuticals, Inc. | APLS | Purchase | Common Stock | 11.7k | $29.71 | $347.6k | | 08/29/2019 |
| 02/08/2019 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock option (right to buy) | 95k | $13.85 | $1.3M | | 02/08/2019 |
| 02/16/2018 | Apellis Pharmaceuticals, Inc. | APLS | Grant | Stock Option (right to buy) | 25k | $14.95 | $373.8k | | 02/16/2018 |