| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 34.1k | $110.20 | $3.8M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 86.6k | $29.56 | $2.6M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 70.4k | $36.32 | $2.6M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 240k | $6.70 | $1.6M | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Stock Option (right to buy) | 40k | $0.50 | $20k | | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Common Stock | 14k | $0.00 | $0 | By Stenhouse Family Fund | 06/16/2023 |
| 06/16/2023 | Prometheus Biosciences, Inc. | RXDX | Disposition | Common Stock | 12.8k | $0.00 | $0 | | 06/16/2023 |
| 06/01/2023 | Prometheus Biosciences, Inc. | RXDX | Other (acquisition) | Common Stock | 14k | $0.00 | $0 | By Stenhouse Family Fund | 06/01/2023 |
| 06/01/2023 | Prometheus Biosciences, Inc. | RXDX | Other (disposition) | Common Stock | 14k | $0.00 | $0 | | 06/01/2023 |
| 05/25/2023 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy) | 15k | $11.72 | $175.8k | | 05/25/2023 |
| 05/25/2023 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Common Stock | 9k | $0.00 | $0 | | 05/25/2023 |
| 12/09/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Common Stock | 9.8k | $0.00 | $0 | | 12/09/2022 |
| 12/09/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 34.1k | $110.20 | $3.8M | | 12/09/2022 |
| 05/25/2022 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy) | 15k | $7.40 | $111k | | 05/25/2022 |
| 05/20/2022 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 86.6k | $29.56 | $2.6M | | 05/20/2022 |
| 11/14/2021 | Prometheus Biosciences, Inc. | RXDX | Grant | Stock Option (Right to Buy) | 70.4k | $36.32 | $2.6M | | 11/14/2021 |
| 05/21/2021 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy) | 12.5k | $35.49 | $443.6k | | 05/21/2021 |
| 03/16/2021 | Prometheus Biosciences, Inc. | RXDX | Purchase | Common Stock | 14k | $19.00 | $266k | | 03/16/2021 |
| 04/03/2020 | EXACT SCIENCES CORP | EXAS | Sale | Common Stock | 11.9k | $56.69 | $677.3k | | 04/02/2020 |
| 04/02/2020 | EXACT SCIENCES CORP | EXAS | Exercise | Restricted Stock Units | 25k | $0.00 | $0 | | 04/02/2020 |
| 03/17/2020 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy) | 20k | $29.84 | $596.8k | | 03/17/2020 |
| 02/27/2020 | EXACT SCIENCES CORP | EXAS | Sale | Common Stock | 1.1k | $80.27 | $84.4k | | 02/26/2020 |
| 02/26/2020 | EXACT SCIENCES CORP | EXAS | Exercise | Restricted Stock Units | 3.3k | $0.00 | $0 | | 02/26/2020 |
| 02/14/2020 | EXACT SCIENCES CORP | EXAS | Grant | Restricted Stock Units | 14.1k | $0.00 | $0 | | 02/14/2020 |
| 02/14/2020 | EXACT SCIENCES CORP | EXAS | Grant | Stock Option (right to buy) | 11.4k | $98.18 | $1.1M | | 02/14/2020 |
| 04/03/2019 | EXACT SCIENCES CORP | EXAS | Sale | Common Stock | 11.2k | $92.54 | $1M | | 04/02/2019 |
| 04/02/2019 | EXACT SCIENCES CORP | EXAS | Exercise | Restricted Stock Units | 25k | $0.00 | $0 | | 04/02/2019 |
| 02/26/2019 | EXACT SCIENCES CORP | EXAS | Grant | Stock Option (right to buy) | 10.8k | $92.62 | $999k | | 02/26/2019 |
| 02/26/2019 | EXACT SCIENCES CORP | EXAS | Grant | Restricted Stock Units | 13.1k | $0.00 | $0 | | 02/26/2019 |
| 04/02/2018 | EXACT SCIENCES CORP | EXAS | Grant | Restricted Stock Units | 75k | $0.00 | $0 | | 04/02/2018 |