| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/02/2023 | Zangerle John Adam | Sr. VP, Gen Counsel, and Sec. | Payment of Exercise | Ordinary Shares | 61 | $215.50 | $13.1k | | 10/02/2023 |
| 10/02/2023 | Carestio Daniel A | President and CEO | Payment of Exercise | Ordinary Shares | 130 | $215.50 | $28k | | 10/02/2023 |
| 10/02/2023 | Burton Karen L | VP, Controller & CAO | Payment of Exercise | Ordinary Shares | 26 | $215.50 | $5.6k | | 10/02/2023 |
| 10/02/2023 | Xilas Andrew | SVP and GM, Dental | Payment of Exercise | Ordinary Shares | 85 | $215.50 | $18.3k | | 10/02/2023 |
| 10/02/2023 | Madsen Julia | Senior VP, Life Sciences | Payment of Exercise | Ordinary Shares | 171 | $215.50 | $36.9k | | 10/02/2023 |
| 08/03/2023 | Alegria Esther M. | Director | Grant | Career Restricted Stock Units | 1k | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Martin Paul Edward | Director | Grant | Career Restricted Stock Units | 1k | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Shah Nirav R | Director | Grant | Director Stock Option (right to buy) | 1.5k | $225.50 | $348.2k | | 08/03/2023 |
| 08/03/2023 | Shah Nirav R | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Steeves Richard Martin | Director | Grant | Career Restricted Stock Units | 364 | $225.50 | $82.1k | | 08/03/2023 |
| 08/03/2023 | Steeves Richard Martin | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Steeves Richard Martin | Director | Grant | Director Stock Option (right to buy) | 195 | $76.72 | $15k | | 08/03/2023 |
| 08/03/2023 | Steeves Richard Martin | Director | Grant | Director Stock Option (right to buy) | 1.5k | $225.50 | $348.4k | | 08/03/2023 |
| 08/03/2023 | Sohi Mohsen | Director | Grant | Director Stock Option (right to buy) | 2.4k | $225.50 | $550.9k | | 08/03/2023 |
| 08/03/2023 | Sohi Mohsen | Director | Grant | Career Restricted Stock Units | 831 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Sohi Mohsen | Director | Grant | Career Restricted Stock Units | 279 | $225.50 | $62.9k | | 08/03/2023 |
| 08/03/2023 | Breeden Richard C | Director | Grant | Director Stock Option (right to buy) | 1.5k | $225.50 | $348.2k | | 08/03/2023 |
| 08/03/2023 | Breeden Richard C | Director | Grant | Director Stock Option (right to buy) | 326 | $76.72 | $25k | | 08/03/2023 |
| 08/03/2023 | Breeden Richard C | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | Breeden Richard C | Director | Grant | Career Restricted Stock Units | 364 | $225.50 | $82.1k | | 08/03/2023 |
| 08/03/2023 | FELDMANN CYNTHIA L | Director | Grant | Director Stock Options (right to buy) | 1.5k | $225.50 | $348.2k | | 08/03/2023 |
| 08/03/2023 | FELDMANN CYNTHIA L | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | KOSECOFF JACQUELINE B | Director | Grant | Career Restricted Stock Units | 364 | $225.50 | $82.1k | | 08/03/2023 |
| 08/03/2023 | KOSECOFF JACQUELINE B | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | KOSECOFF JACQUELINE B | Director | Grant | Director Stock Option (right to buy) | 261 | $76.72 | $20k | | 08/03/2023 |
| 08/03/2023 | KOSECOFF JACQUELINE B | Director | Grant | Director Stock Option (right to buy) | 1.5k | $225.50 | $348.2k | | 08/03/2023 |
| 08/03/2023 | HOLLAND CHRISTOPHER S | Director | Grant | Director Stock Option (right to buy) | 1.5k | $225.50 | $348.2k | | 08/03/2023 |
| 08/03/2023 | HOLLAND CHRISTOPHER S | Director | Grant | Career Restricted Stock Units | 525 | $0.00 | $0 | | 08/03/2023 |
| 06/02/2023 | Burton Karen L | VP, Controller & CAO | Payment of Exercise | Ordinary Shares | 127 | $205.47 | $26.1k | | 06/02/2023 |
| 06/02/2023 | Zangerle John Adam | Sr. VP, Gen Counsel, and Sec. | Payment of Exercise | Ordinary Shares | 498 | $205.47 | $102.3k | | 06/02/2023 |
| 06/02/2023 | Carestio Daniel A | President and CEO | Payment of Exercise | Ordinary Shares | 2.4k | $205.47 | $497.6k | | 06/02/2023 |
| 06/02/2023 | Madsen Julia | Senior VP, Life Sciences | Payment of Exercise | Ordinary Shares | 247 | $205.47 | $50.8k | | 06/02/2023 |
| 06/02/2023 | Xilas Andrew | SVP and GM, Dental | Payment of Exercise | Ordinary Shares | 103 | $205.47 | $21.2k | | 06/02/2023 |
| 05/31/2023 | Alegria Esther M. | Director | Grant | Career Restricted Stock Units | 371 | $0.00 | $0 | | 05/31/2023 |
| 05/31/2023 | Fraser Mary Clare | SVP & Chief HRO | Grant | Ordinary Shares | 2.3k | $0.00 | $0 | | 05/31/2023 |
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