| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 91.7k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 106.5k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 150.8k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 483.7k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 296.4k | $0.00 | $0 | Impresa Fund III Limited Partnership | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Common Stock | 4.9k | $0.00 | $0 | F-Prime Capital Partners Healthcare Advisors Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series D Preferred Stock | 91.7k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series C Preferred Stock | 106.5k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 150.8k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series B-1 Preferred Stock | 483.7k | $0.00 | $0 | F-Prime Capital Partners Healthcare Fund V LP | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 296.4k | $0.00 | $0 | Impresa Fund III Limited Partnership | 07/25/2023 |
| 07/25/2023 | FMR LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 4.9k | $0.00 | $0 | F-Prime Capital Partners Healthcare Advisors Fund V LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Common Stock | 2.5M | $0.00 | $0 | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Common Stock | 192.5k | $0.00 | $0 | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Common Stock | 84.3k | $0.00 | $0 | By Versant Ophthalmic Affiliates Fund I, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Common Stock | 76.1k | $0.00 | $0 | By Versant Affiliates Fund V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Common Stock | 275k | $0.00 | $0 | By Versant Vantage II, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Purchase | Common Stock | 197.5k | $12.00 | $2.4M | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Purchase | Common Stock | 15k | $12.00 | $180.3k | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Purchase | Common Stock | 6.6k | $12.00 | $78.9k | By Versant Ophthalmic Affiliates Fund I, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Purchase | Common Stock | 5.9k | $12.00 | $71.3k | By Versant Affiliates Fund V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series A Preferred Stock | 7.9M | $0.00 | $0 | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series A Preferred Stock | 601.1k | $0.00 | $0 | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series A Preferred Stock | 263.3k | $0.00 | $0 | By Versant Ophthalmic Affiliates Fund I, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series A Preferred Stock | 237.6k | $0.00 | $0 | By Versant Affiliates Fund V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-1 Preferred Stock | 3.5M | $0.00 | $0 | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-1 Preferred Stock | 268.7k | $0.00 | $0 | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-1 Preferred Stock | 117.7k | $0.00 | $0 | By Versant Ophthalmic Affiliates Fund I, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-1 Preferred Stock | 106.2k | $0.00 | $0 | By Versant Affiliates Fund V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 7.7M | $0.00 | $0 | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 582.2k | $0.00 | $0 | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 255.1k | $0.00 | $0 | By Versant Ophthalmic Affiliates Fund I, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series B-2 Preferred Stock | 230.1k | $0.00 | $0 | By Versant Affiliates Fund V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series C Preferred Stock | 1.1M | $0.00 | $0 | By Versant Venture Capital V, L.P. | 07/25/2023 |
| 07/25/2023 | Versant Ventures V, LLC | 10% Owner | Conversion | Series C Preferred Stock | 85.2k | $0.00 | $0 | By Versant Venture Capital V (Canada) LP | 07/25/2023 |
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