| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/16/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Common Stock | 15k | $0.00 | $0 | | 01/16/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Exercise | Stock Option (Right to Buy) | 13k | $91.79 | $1.2M | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 600 | $277.91 | $166.7k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $279.10 | $111.6k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.8k | $280.66 | $505.2k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.7k | $281.97 | $748.9k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.6k | $282.97 | $743.6k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.5k | $283.85 | $439.7k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 829 | $285.15 | $236.4k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2k | $285.74 | $582.3k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $286.62 | $114.6k | | 01/03/2023 |
| 01/03/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 100 | $287.86 | $28.8k | | 01/03/2023 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Exercise | Stock Option (Right to Buy) | 7k | $91.79 | $642.5k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 200 | $283.61 | $56.7k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 200 | $281.79 | $56.4k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 200 | $280.41 | $56.1k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.1k | $279.46 | $307.4k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 361 | $277.77 | $100.3k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 100 | $276.40 | $27.6k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 100 | $275.24 | $27.5k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $274.70 | $109.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 539 | $273.48 | $147.4k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.5k | $272.74 | $409.1k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 800 | $271.27 | $217k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 700 | $270.25 | $189.2k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 300 | $268.99 | $80.7k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 500 | $267.88 | $133.9k | | 12/23/2022 |
| 08/10/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 25k | $73.75 | $1.8M | | 08/10/2022 |
| 02/22/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 45k | $87.09 | $3.9M | | 02/22/2022 |
| 02/22/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 32k | $119.49 | $3.8M | | 02/22/2021 |
| 08/06/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 20k | $103.10 | $2.1M | | 08/06/2020 |
| 03/05/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 32k | $91.79 | $2.9M | | 03/05/2020 |