| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/16/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Common Stock | 15k | $0.00 | $0 | | 01/16/2023 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 3k | $274.56 | $828.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 811 | $275.70 | $223.6k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 700 | $276.67 | $193.7k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 700 | $277.83 | $194.5k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 3k | $279.15 | $838.3k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.6k | $279.96 | $733.5k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1000 | $280.92 | $280.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $282.13 | $112.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $283.43 | $113.4k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 100 | $284.65 | $28.5k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Exercise | Stock Option (Right to Buy) | 30k | $60.26 | $1.8M | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.1k | $270.56 | $559.8k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.5k | $269.61 | $397.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.9k | $268.50 | $513.6k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.1k | $267.47 | $296.1k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 593 | $266.04 | $157.8k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.5k | $273.54 | $675.9k | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 5.5k | $272.68 | $1.5M | | 12/23/2022 |
| 12/23/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.1k | $271.54 | $565.9k | | 12/23/2022 |
| 02/22/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 45k | $87.09 | $3.9M | | 02/22/2022 |
| 02/22/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to Buy) | 24k | $119.49 | $2.9M | | 02/22/2021 |