| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/25/2023 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy) | 15k | $11.72 | $175.8k | | 05/25/2023 |
| 05/25/2023 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Common Stock | 9k | $0.00 | $0 | | 05/25/2023 |
| 01/06/2023 | ANAPTYSBIO, INC | ANAB | Grant | Stock Option (right to buy) | 10.6k | $23.23 | $246.2k | | 01/06/2023 |
| 01/06/2023 | ANAPTYSBIO, INC | ANAB | Grant | Restricted Stock Unit | 3.9k | $0.00 | $0 | | 01/06/2023 |
| 01/03/2023 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Grant | Stock Option (Right to buy) | 10k | $0.00 | $0 | | 01/03/2023 |
| 09/22/2022 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option (Right to Buy | 20k | $10.02 | $200.4k | | 09/22/2022 |
| 02/10/2022 | ANAPTYSBIO, INC | ANAB | Grant | Stock Option (right to buy) | 9.2k | $30.44 | $280k | | 02/10/2022 |
| 01/03/2022 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Grant | Stock Option (Right to buy) | 10k | $0.00 | $0 | | 01/03/2022 |
| 02/10/2021 | ANAPTYSBIO, INC | ANAB | Grant | Stock Option (right to buy) | 11k | $29.70 | $326.7k | | 02/10/2021 |
| 01/04/2021 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Grant | Stock Option (Right to buy) | 7.6k | $0.00 | $0 | | 01/04/2021 |
| 12/11/2020 | Frazier Lifesciences Acquisition Corp | | Grant | Class A Ordinary Shares | 501k | $10.00 | $5M | | 12/11/2020 |
| 12/11/2020 | Frazier Lifesciences Acquisition Corp | | Purchase | Class A Ordinary Shares | 1000k | $10.00 | $10M | | 12/11/2020 |
| 12/11/2020 | Frazier Lifesciences Acquisition Corp | | Grant | Warrants | 167k | $11.50 | $1.9M | | 12/11/2020 |
| 12/11/2020 | Frazier Lifesciences Acquisition Corp | | Grant | Warrants | 333.3k | $11.50 | $3.8M | | 12/11/2020 |
| 11/17/2020 | Allena Pharmaceuticals, Inc. | ALNA | Grant | Stock Option (Right to Buy) | 14k | $1.45 | $20.3k | | 11/17/2020 |
| 11/16/2020 | ANAPTYSBIO, INC | ANAB | Other (disposition) | Common Stock | 344.9k | $0.00 | $0 | By: Frazier Healthcare VII, L.P. | 11/16/2020 |
| 11/16/2020 | ANAPTYSBIO, INC | ANAB | Other (disposition) | Common Stock | 98.3k | $0.00 | $0 | By: Frazier Healthcare VII-A, L.P. | 11/16/2020 |
| 11/16/2020 | ANAPTYSBIO, INC | ANAB | Other (acquisition) | Common Stock | 22.6k | $0.00 | $0 | | 11/16/2020 |
| 11/16/2020 | ANAPTYSBIO, INC | ANAB | Other (acquisition) | Common Stock | 26.4k | $0.00 | $0 | | 11/16/2020 |
| 11/16/2020 | ANAPTYSBIO, INC | ANAB | Other (disposition) | Common Stock | 973.6k | $0.00 | $0 | By: Frazier Healthcare V, L.P. | 11/16/2020 |
| 05/21/2020 | Phathom Pharmaceuticals, Inc. | PHAT | Grant | Stock Option | 10k | $36.85 | $368.5k | | 05/21/2020 |
| 03/31/2020 | Aptinyx Inc. | APTX | Grant | Common Stock | 5k | $2.16 | $10.7k | See Footnote | 03/31/2020 |
| 02/12/2020 | ANAPTYSBIO, INC | ANAB | Grant | Director Stock Option (Right to Buy) | 11k | $16.56 | $182.2k | | 02/12/2020 |
| 01/02/2020 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Grant | Stock Option (Right to buy) | 7.6k | $0.00 | $0 | | 01/02/2020 |
| 12/31/2019 | Aptinyx Inc. | APTX | Grant | Stock Option (Right to Buy) | 5k | $3.42 | $17.2k | | 12/31/2019 |
| 09/30/2019 | Aptinyx Inc. | APTX | Grant | Stock Option (Right to Buy) | 5.2k | $3.49 | $18k | | 09/30/2019 |
| 06/28/2019 | Aptinyx Inc. | APTX | Grant | Stock Option (Right to Buy) | 5.4k | $3.34 | $18.1k | | 06/28/2019 |
| 06/05/2019 | Allena Pharmaceuticals, Inc. | ALNA | Grant | Stock Option (Right to Buy) | 14k | $5.59 | $78.3k | | 06/05/2019 |
| 05/15/2019 | Aptinyx Inc. | APTX | Grant | Stock Option (Right to Buy) | 40k | $3.73 | $149.2k | | 05/15/2019 |
| 03/29/2019 | Aptinyx Inc. | APTX | Grant | Stock Option (Right to Buy) | 4.4k | $4.05 | $18k | | 03/29/2019 |
| 02/08/2019 | ANAPTYSBIO, INC | ANAB | Grant | Director Stock Option (Right to Buy) | 6k | $68.89 | $413.3k | | 02/08/2019 |
| 01/18/2019 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Purchase | Common Stock | 372.4k | $5.37 | $2M | By Frazier Life Sciences VIII, L.P. | 01/18/2019 |
| 01/18/2019 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Purchase | Warrant (Right to Buy) | 145.3k | $12.74 | $1.9M | By Frazier Life Sciences VIII, L.P. | 01/18/2019 |
| 01/18/2019 | Entasis Therapeutics Holdings Inc. | ETTX | Grant | Stock Option (right to buy) | 15k | $5.66 | $84.9k | | 01/18/2019 |
| 01/02/2019 | ALPINE IMMUNE SCIENCES, INC. | NVLS | Grant | Stock Option (Right to buy) | 7.6k | $0.00 | $0 | | 01/02/2019 |
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