| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/07/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 3.1k | $183.58 | $571.3k | | 08/03/2023 |
| 08/07/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 814 | $184.65 | $150.3k | | 08/03/2023 |
| 08/07/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 240 | $185.32 | $44.5k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 658 | $184.70 | $121.5k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 1.6k | $185.54 | $295.6k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 945 | $186.39 | $176.1k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 86 | $187.37 | $16.1k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 15 | $188.40 | $2.8k | | 08/03/2023 |
| 08/04/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 164 | $189.31 | $31k | | 08/03/2023 |
| 08/03/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 4.5k | $0.00 | $0 | | 08/03/2023 |
| 08/03/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 3.1k | $0.00 | $0 | | 08/03/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 204 | $195.46 | $39.9k | | 04/26/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 103 | $196.62 | $20.3k | | 04/26/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 715 | $198.03 | $141.6k | | 04/26/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 385 | $199.54 | $76.8k | | 04/26/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 955 | $200.35 | $191.3k | | 04/26/2023 |
| 04/28/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 93 | $201.30 | $18.7k | | 04/26/2023 |
| 04/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 151 | $193.18 | $29.2k | | 04/26/2023 |
| 04/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 700 | $193.93 | $135.8k | | 04/26/2023 |
| 04/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 779 | $194.94 | $151.9k | | 04/26/2023 |
| 04/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 80 | $195.65 | $15.7k | | 04/26/2023 |
| 04/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 129 | $197.08 | $25.4k | | 04/26/2023 |
| 04/26/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 4.3k | $0.00 | $0 | | 04/26/2023 |
| 03/03/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 18.1k | $200.00 | $3.6M | | 03/03/2023 |
| 03/03/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 2.5k | $96.45 | $241.1k | | 03/03/2023 |
| 02/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Restricted Stock Units | 5.7k | $0.00 | $0 | | 02/27/2023 |
| 02/27/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 11.8k | $190.01 | $2.3M | | 02/27/2023 |
| 08/04/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 4.6k | $189.76 | $873.5k | | 08/03/2022 |
| 08/04/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 165 | $205.87 | $34k | | 08/03/2022 |
| 08/04/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 172 | $209.91 | $36.1k | | 08/03/2022 |
| 08/04/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 146 | $210.02 | $30.7k | | 08/03/2022 |
| 08/03/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 4.5k | $0.00 | $0 | | 08/03/2022 |
| 08/03/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 3.7k | $0.00 | $0 | | 08/03/2022 |
| 08/03/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 3.1k | $0.00 | $0 | | 08/03/2022 |
| 06/15/2022 | SQZ Biotechnologies Co | SQZ | Grant | Stock Option | 20k | $3.23 | $64.6k | | 06/15/2022 |
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