| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/17/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 668 | $13.86 | $9.3k | | 08/15/2023 |
| 08/15/2023 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 1.2k | $0.00 | $0 | | 08/15/2023 |
| 08/15/2023 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 1.4k | $0.00 | $0 | | 08/15/2023 |
| 06/05/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 1.2k | $16.00 | $19.7k | | 06/05/2023 |
| 05/16/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 692 | $13.12 | $9.1k | | 05/15/2023 |
| 05/15/2023 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 1.2k | $0.00 | $0 | | 05/15/2023 |
| 05/15/2023 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 1.4k | $0.00 | $0 | | 05/15/2023 |
| 03/10/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 10k | $18.05 | $180.5k | | 03/10/2023 |
| 01/17/2023 | Day One Biopharmaceuticals, Inc. | | Grant | Stock Option (right to buy Common Stock) | 72k | $20.87 | $1.5M | | 01/17/2023 |
| 01/17/2023 | Day One Biopharmaceuticals, Inc. | | Grant | Restricted Stock Units | 23k | $0.00 | $0 | | 01/17/2023 |
| 01/10/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 7.5k | $22.75 | $170.6k | | 01/10/2023 |
| 01/10/2023 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 2.5k | $23.20 | $58k | | 01/10/2023 |
| 12/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 9.1k | $21.38 | $194.6k | | 12/01/2022 |
| 12/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 900 | $22.16 | $19.9k | | 12/01/2022 |
| 11/16/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 377 | $21.46 | $8.1k | | 11/15/2022 |
| 11/15/2022 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 1.2k | $0.00 | $0 | | 11/15/2022 |
| 11/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 10k | $20.01 | $200k | | 11/01/2022 |
| 10/03/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 10k | $19.99 | $199.9k | | 10/03/2022 |
| 09/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 8.4k | $23.14 | $194.6k | | 09/01/2022 |
| 09/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 1.6k | $23.79 | $37.8k | | 09/01/2022 |
| 08/16/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 941 | $24.31 | $22.9k | | 08/15/2022 |
| 08/15/2022 | Day One Biopharmaceuticals, Inc. | | Exercise | Restricted Stock Units | 3.6k | $0.00 | $0 | | 08/15/2022 |
| 08/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 10k | $16.88 | $168.8k | | 08/01/2022 |
| 07/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 5.8k | $18.24 | $106.2k | | 07/01/2022 |
| 07/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 3.3k | $19.23 | $63.6k | | 07/01/2022 |
| 07/01/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 867 | $19.95 | $17.3k | | 07/01/2022 |
| 06/15/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 50k | $16.26 | $813.2k | | 06/15/2022 |
| 01/18/2022 | Day One Biopharmaceuticals, Inc. | | Grant | Stock Option (right to buy Common Stock) | 135k | $14.26 | $1.9M | | 01/18/2022 |
| 01/18/2022 | Day One Biopharmaceuticals, Inc. | | Grant | Restricted Stock Units | 19k | $0.00 | $0 | | 01/18/2022 |
| 01/03/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 6.7k | $16.95 | $113.1k | | 01/03/2022 |
| 01/03/2022 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 3.3k | $17.41 | $57.9k | | 01/03/2022 |
| 12/01/2021 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 5.1k | $16.62 | $84.6k | | 12/01/2021 |
| 12/01/2021 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 4.5k | $17.81 | $80.2k | | 12/01/2021 |
| 12/01/2021 | Day One Biopharmaceuticals, Inc. | | Sale | Common Stock | 409 | $18.24 | $7.5k | | 12/01/2021 |
| 10/22/2021 | Day One Biopharmaceuticals, Inc. | | Gift | Common Stock | 1000k | $0.00 | $0 | | 12/01/2021 |
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