| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/22/2023 | Gregory Philip D | Chief Scientific Officer | Sale | Common Stock | 6.2k | $5.49 | $33.8k | | 08/22/2023 |
| 08/22/2023 | Leschly Nick | President and CEO | Sale | Common Stock | 9.3k | $5.49 | $51.1k | | 08/22/2023 |
| 08/22/2023 | Baird William D III | CFO | Sale | Common Stock | 7k | $5.49 | $38.6k | | 08/22/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 100k | $5.85 | $585k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 86.4k | $5.96 | $515k | | 08/10/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 86.4k | $5.96 | $515k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 179k | $5.94 | $1.1M | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 50k | $5.80 | $290k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 100k | $5.85 | $585k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 100k | $5.96 | $596k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 86.4k | $5.96 | $515k | | 08/10/2023 |
| 08/10/2023 | Kynam Capital Management, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 86.4k | $5.96 | $515k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 100k | $5.96 | $596k | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 179k | $5.94 | $1.1M | See Footnote | 08/10/2023 |
| 08/10/2023 | Kynam Global Healthcare Master Fund, LP | 10% Owner | Purchase | Common Stock, par value $0.0001 per share | 50k | $5.80 | $290k | See Footnote | 08/10/2023 |
| 08/03/2023 | Baird William D III | CFO | Sale | Common Stock | 6.9k | $6.13 | $42.3k | | 08/03/2023 |
| 08/03/2023 | Gregory Philip D | Chief Scientific Officer | Sale | Common Stock | 4k | $6.13 | $24.3k | | 08/03/2023 |
| 08/03/2023 | Leschly Nick | President and CEO | Sale | Common Stock | 9.1k | $6.13 | $55.5k | | 08/03/2023 |
| 06/13/2023 | Maus Marcela V. | Director | Grant | | 8.4k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | Maus Marcela V. | Director | Grant | Stock Option (right to buy) | 16.9k | $11.81 | $199.6k | | 06/13/2023 |
| 06/13/2023 | Glickman Sarah JS | Director | Grant | | 8.4k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | Glickman Sarah JS | Director | Grant | Stock Option (right to buy) | 16.9k | $11.81 | $199.6k | | 06/13/2023 |
| 06/13/2023 | LYNCH DANIEL | Director | Grant | | 8.4k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | LYNCH DANIEL | Director | Grant | Stock Option (right to buy) | 16.9k | $11.81 | $199.6k | | 06/13/2023 |
| 06/13/2023 | Wei Lin | Director | Grant | | 4.2k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | Wei Lin | Director | Grant | Stock Option (right to buy) | 8.4k | $11.81 | $99.8k | | 06/13/2023 |
| 06/13/2023 | Ibrahim Ramy | Director | Grant | | 8.4k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | Ibrahim Ramy | Director | Grant | Stock Option (right to buy) | 16.9k | $11.81 | $199.6k | | 06/13/2023 |
| 06/13/2023 | Torres Denice | Director | Grant | | 8.4k | $0.00 | $0 | | 06/13/2023 |
| 06/13/2023 | Torres Denice | Director | Grant | Stock Option (right to buy) | 16.9k | $11.81 | $199.6k | | 06/13/2023 |
| 03/07/2023 | Wei Lin | Director | Grant | Stock Option (Right to buy) | 33.4k | $10.91 | $364.4k | | 03/07/2023 |
| 03/07/2023 | Wei Lin | Director | Grant | | 16.6k | $0.00 | $0 | | 03/07/2023 |
| 02/07/2023 | Heffron Nicola | COO | Sale | Common Stock | 60 | $14.70 | $882 | | 02/07/2023 |
| 01/09/2023 | Leschly Nick | President and CEO | Sale | Common Stock | 3k | $10.33 | $30.8k | | 01/09/2023 |
| 01/09/2023 | Baird William D III | CFO | Sale | Common Stock | 3.2k | $10.33 | $33.3k | | 01/09/2023 |
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