| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/17/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 6.4k | $26.28 | $168.1k | | 08/17/2023 |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 1.7k | $28.36 | $48.4k | | 06/28/2023 |
| 06/28/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Performance share units | 5.8k | $0.00 | $0 | | 06/28/2023 |
| 02/14/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 643 | $28.44 | $18.3k | | 02/10/2023 |
| 02/10/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 1.8k | $0.00 | $0 | | 02/10/2023 |
| 12/28/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 2.6k | $28.48 | $74k | | 12/23/2022 |
| 12/23/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 8.8k | $0.00 | $0 | | 12/23/2022 |
| 02/22/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 215 | $29.08 | $6.3k | | 02/22/2022 |
| 02/22/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 724 | $0.00 | $0 | | 02/22/2022 |
| 02/14/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 2.2k | $30.50 | $65.7k | | 02/14/2022 |
| 02/14/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 1.7k | $0.00 | $0 | | 02/14/2022 |
| 02/14/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 5.2k | $0.00 | $0 | | 02/14/2022 |
| 02/10/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 643 | $31.43 | $20.2k | | 02/10/2022 |
| 02/10/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 1.8k | $0.00 | $0 | | 02/10/2022 |