| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/24/2023 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 25.8k | $11.94 | $307.8k | | 05/24/2023 |
| 05/25/2022 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock option (right to buy) | 63k | $5.37 | $338.4k | | 05/25/2022 |
| 06/16/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 12.9k | $27.90 | $359.5k | | 06/16/2021 |
| 02/12/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Sale | Common Stock | 101.7k | $50.40 | $5.1M | | 02/12/2021 |
| 08/04/2020 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 97.8k | $3.89 | $380.4k | | 08/04/2020 |
| 05/22/2018 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 25k | $2.61 | $65.2k | | 05/22/2018 |
| 05/24/2017 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 25k | $3.81 | $95.2k | | 05/24/2017 |
| 05/17/2016 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 25k | $8.98 | $224.5k | | 05/17/2016 |
| 05/21/2013 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 25k | $2.54 | $63.5k | | 05/21/2013 |
| 09/26/2012 | Anacor Pharmaceuticals, Inc. | ANAC | Sale | Common Stock | 10k | $6.58 | $65.8k | MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999 | 09/26/2012 |
| 09/24/2012 | Anacor Pharmaceuticals, Inc. | ANAC | Sale | Common Stock | 10k | $6.35 | $63.5k | MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999 | 09/21/2012 |
| 09/21/2012 | Anacor Pharmaceuticals, Inc. | ANAC | Sale | Common Stock | 10k | $6.30 | $63k | MCADAMS-SHAPIRO FAMILY TRUST DTD MAY 24, 1999 | 09/21/2012 |
| 09/12/2012 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | Grant | Stock Option (right to buy) | 35k | $1.93 | $67.6k | | 09/12/2012 |
| 05/25/2011 | Anacor Pharmaceuticals, Inc. | ANAC | Grant | Stock Option (right to buy) | 15k | $6.74 | $101.1k | | 05/25/2011 |
| 04/01/2011 | GEN PROBE INC | GPRO | Grant | Common Stock | 49 | $66.06 | $3.2k | | 04/01/2011 |
| 01/03/2011 | GEN PROBE INC | GPRO | Grant | Common Stock | 54 | $59.40 | $3.2k | | 01/03/2011 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Series E Preferred Stock | 800 | $0.00 | $0 | By McAdams Shapiro Family Trust | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Series D Preferred Stock | 14.4k | $0.00 | $0 | By McAdams Shapiro Family Trust | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Series C Preferred Stock | 16.9k | $0.00 | $0 | | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Series A-2 Preferred Stock | 12.7k | $0.00 | $0 | | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Common Stock | 800 | $0.00 | $0 | By McAdams Shapiro Family Trust | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Common Stock | 14.4k | $0.00 | $0 | By McAdams Shapiro Family Trust | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Common Stock | 16.9k | $0.00 | $0 | | 11/30/2010 |
| 11/30/2010 | Anacor Pharmaceuticals, Inc. | ANAC | Conversion | Common Stock | 12.7k | $0.00 | $0 | | 11/30/2010 |
| 07/01/2010 | GEN PROBE INC | GPRO | Grant | Common Stock | 71 | $0.00 | $0 | | 07/01/2010 |
| 04/01/2010 | GEN PROBE INC | GPRO | Grant | Common Stock | 63 | $0.00 | $0 | | 04/01/2010 |