| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 08/10/2023 | Aceragen, Inc. | IDRA | Sale | Common Stock | 3.3k | $0.53 | $1.8k | | 08/10/2023 |
| 06/02/2023 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted Stock Units | 4.5k | $0.00 | $0 | | 06/01/2023 |
| 06/01/2023 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 15.8k | $8.70 | $137k | | 06/01/2023 |
| 06/01/2023 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 4.7k | $0.00 | $0 | | 06/01/2023 |
| 05/31/2023 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | Common Stock | 680 | $8.27 | $5.6k | | 05/31/2023 |
| 02/28/2023 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | | 635 | $8.85 | $5.6k | | 02/28/2023 |
| 11/30/2022 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | | 421 | $13.36 | $5.6k | | 11/30/2022 |
| 08/31/2022 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | | 404 | $13.90 | $5.6k | | 08/31/2022 |
| 07/06/2022 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 124k | $0.43 | $53.7k | | 07/06/2022 |
| 06/07/2022 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | Common Stock | 12.9k | $0.00 | $0 | | 06/07/2022 |
| 06/07/2022 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | | 30k | $10.79 | $323.9k | | 06/07/2022 |
| 06/03/2022 | Aclaris Therapeutics, Inc. | ACRS | Exercise | Restricted Stock Units | 3.4k | $0.00 | $0 | | 06/02/2022 |
| 06/02/2022 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 15.8k | $14.48 | $228.1k | | 06/02/2022 |
| 06/02/2022 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 4.5k | $0.00 | $0 | | 06/02/2022 |
| 04/01/2022 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 99k | $0.54 | $53k | | 04/01/2022 |
| 01/24/2022 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 25k | $0.57 | $14.4k | | 01/24/2022 |
| 11/24/2021 | BIOCRYST PHARMACEUTICALS INC | BCRX | Purchase | Common Stock | 7.5k | $12.19 | $91.4k | | 11/24/2021 |
| 07/26/2021 | BIOCRYST PHARMACEUTICALS INC | BCRX | Grant | Non-Qualified Stock Option | 66.7k | $17.25 | $1.2M | | 07/26/2021 |
| 07/08/2021 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 124k | $1.11 | $137.6k | | 07/08/2021 |
| 06/03/2021 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (Right to Buy) | 12.2k | $21.90 | $268.3k | | 06/03/2021 |
| 06/03/2021 | Aclaris Therapeutics, Inc. | ACRS | Grant | Restricted Stock Units | 3.4k | $0.00 | $0 | | 06/03/2021 |
| 01/12/2021 | Aceragen, Inc. | IDRA | Sale | Common Stock | 3.2k | $4.20 | $13.5k | | 01/08/2021 |
| 01/08/2021 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 95k | $4.28 | $406.6k | | 01/08/2021 |
| 01/05/2021 | Aceragen, Inc. | IDRA | Sale | Common Stock | 2.7k | $3.91 | $10.7k | | 01/05/2021 |
| 12/22/2020 | Aceragen, Inc. | IDRA | Sale | Common Stock | 37.2k | $4.32 | $160.5k | | 12/18/2020 |
| 12/18/2020 | Aceragen, Inc. | IDRA | Grant | Common Stock | 128.2k | $0.00 | $0 | | 12/18/2020 |
| 07/21/2020 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 92k | $2.48 | $228.2k | | 07/21/2020 |
| 06/04/2020 | Aclaris Therapeutics, Inc. | ACRS | Grant | Option Grant (right to buy) | 16.5k | $1.41 | $23.3k | | 06/04/2020 |
| 01/10/2020 | Aceragen, Inc. | IDRA | Grant | Common Stock | 37k | $0.00 | $0 | | 01/10/2020 |
| 01/10/2020 | Aceragen, Inc. | IDRA | Grant | Stock Option (Right to Buy) | 92k | $1.79 | $164.7k | | 01/10/2020 |
| 01/07/2020 | Aceragen, Inc. | IDRA | Sale | Common Stock | 3k | $1.78 | $5.4k | | 01/07/2020 |
| 01/07/2020 | Aceragen, Inc. | IDRA | Sale | Common Stock | 3k | $1.78 | $5.4k | | 01/07/2020 |
| 01/07/2020 | Aclaris Therapeutics, Inc. | ACRS | Grant | Stock Option (right to buy) | 22k | $1.85 | $40.7k | | 01/07/2020 |
| 12/17/2019 | Spark Therapeutics, Inc. | ONCE | Other | Common Stock | 3k | $114.50 | $343.5k | | 12/17/2019 |
| 12/17/2019 | Spark Therapeutics, Inc. | ONCE | Disposition | Stock Option (Right to Buy) | 4k | $81.53 | $326.1k | | 12/17/2019 |
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