| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/08/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Payment of Exercise | Common Stock | 12.5k | $0.60 | $7.5k | | 02/07/2023 |
| 02/07/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 45.4k | $0.00 | $0 | | 02/07/2023 |
| 01/24/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 250k | $0.00 | $0 | | 01/23/2023 |
| 01/23/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 35.5k | $0.60 | $21.2k | | 01/23/2023 |
| 07/19/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 11.9k | $1.10 | $13.1k | | 07/18/2022 |
| 07/18/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 43.2k | $0.00 | $0 | | 07/18/2022 |
| 06/17/2022 | SCYNEXIS INC | SCYX | Grant | Common Stock | 10k | $0.00 | $0 | | 06/17/2022 |
| 06/17/2022 | SCYNEXIS INC | SCYX | Grant | Stock Option (Right to Buy) | 10k | $1.78 | $17.8k | | 06/17/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 190k | $2.41 | $457.9k | | 01/26/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 120k | $0.00 | $0 | | 01/26/2022 |
| 06/16/2021 | SCYNEXIS INC | SCYX | Grant | Stock Option (Right to Buy) | 10k | $7.51 | $75.1k | | 06/16/2021 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 107.9k | $0.00 | $0 | | 01/21/2021 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 161.9k | $3.58 | $579.5k | | 01/21/2021 |
| 12/21/2020 | SCYNEXIS INC | SCYX | Purchase | Common Stock | 5k | $6.25 | $31.2k | | 12/21/2020 |
| 12/21/2020 | SCYNEXIS INC | SCYX | Grant | Common Stock Warrant | 2.5k | $7.33 | $18.3k | | 12/21/2020 |
| 12/21/2020 | SCYNEXIS INC | SCYX | Grant | Common Stock Warrant | 2.5k | $8.25 | $20.6k | | 12/21/2020 |
| 07/06/2020 | SCYNEXIS INC | SCYX | Grant | Stock Option (Right to Buy) | 55k | $0.73 | $40.2k | | 07/06/2020 |
| 07/06/2020 | SCYNEXIS INC | SCYX | Grant | Stock Option (Right to Buy) | 45k | $0.73 | $32.8k | | 07/06/2020 |
| 01/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 162.5k | $5.05 | $820.5k | | 01/30/2020 |
| 06/18/2019 | SCYNEXIS INC | SCYX | Grant | Stock Option (Right to Buy) | 45k | $1.29 | $58k | | 06/18/2019 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 160k | $3.65 | $584k | | 01/24/2019 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 160k | $3.65 | $584k | | 01/24/2019 |
| 01/21/2019 | SCYNEXIS INC | SCYX | Grant | Stock Option (right to buy) | 70k | $0.74 | $52k | | 01/21/2019 |
| 08/06/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 15k | $5.96 | $89.4k | | 08/06/2018 |
| 01/11/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 81k | $11.71 | $948.5k | | 01/11/2018 |
| 05/18/2017 | Vaxart, Inc. | VXRT | Grant | Stock Option (Right to Buy) | 20k | $0.49 | $9.8k | | 05/18/2017 |
| 05/15/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 1.5k | $19.57 | $29.4k | | 05/12/2017 |
| 05/12/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Purchase | Common Stock | 3.5k | $19.76 | $69.2k | | 05/12/2017 |
| 01/25/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 125k | $18.22 | $2.3M | | 01/25/2017 |
| 08/10/2015 | Zynerba Pharmaceuticals, Inc. | ZYNE | Conversion | Common Stock | 26.6k | $0.00 | $0 | See footnote | 08/10/2015 |
| 08/10/2015 | Zynerba Pharmaceuticals, Inc. | ZYNE | Conversion | Common Stock | 13.3k | $0.00 | $0 | See footnote | 08/10/2015 |
| 08/10/2015 | Zynerba Pharmaceuticals, Inc. | ZYNE | Conversion | Series 1 Convertible Preferred Stock | 50k | $0.00 | $0 | See footnote | 08/10/2015 |
| 08/10/2015 | Zynerba Pharmaceuticals, Inc. | ZYNE | Conversion | Series 1 Convertible Preferred Stock | 25k | $0.00 | $0 | See footnote | 08/10/2015 |
| 08/04/2015 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option | 396.7k | $14.00 | $5.6M | | 08/04/2015 |
| 02/21/2014 | NUPATHE INC. | PATH | Disposition | | 1.3M | $6.80 | $8.6M | | 02/21/2014 |
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