| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/25/2022 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 20k | $1.69 | $33.8k | | 05/25/2022 |
| 05/20/2021 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 15k | $4.03 | $60.4k | | 05/20/2021 |
| 06/11/2020 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 10k | $20.47 | $204.7k | | 06/11/2020 |
| 03/10/2020 | TearLab Corp | TEAR | Grant | Stock Option (right to buy) | 60k | $0.03 | $1.9k | | 03/10/2020 |
| 05/17/2019 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 10k | $15.22 | $152.2k | | 05/17/2019 |
| 05/30/2018 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (right to buy) | 7.5k | $42.09 | $315.7k | | 05/30/2018 |
| 02/07/2018 | TearLab Corp | TEAR | Grant | Stock Option (right to buy) | 20k | $0.40 | $8k | | 02/07/2018 |
| 06/01/2017 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (Right to Buy) | 7.5k | $25.96 | $194.7k | | 06/01/2017 |
| 06/02/2016 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (Right to Buy) | 10k | $5.84 | $58.4k | | 06/02/2016 |
| 06/18/2015 | TearLab Corp | TEAR | Grant | Stock Option (right to buy) | 15k | $2.33 | $35k | | 06/18/2015 |
| 05/28/2015 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (Right to Buy) | 10k | $15.90 | $159k | | 05/28/2015 |
| 05/28/2015 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Option (Right to Buy) | 10k | $15.90 | $159k | | 05/28/2015 |
| 07/10/2014 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Options (Right to Buy) | 64k | $0.00 | $0 | | 07/10/2014 |
| 07/10/2014 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Options (Right to Buy) | 64k | $0.00 | $0 | | 07/10/2014 |
| 07/10/2014 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Disposition | Stock Options (Right to Buy) | 7k | $0.00 | $0 | | 07/10/2014 |
| 07/10/2014 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Options (Right to Buy) | 64k | $0.00 | $0 | | 07/10/2014 |
| 06/11/2014 | TearLab Corp | TEAR | Grant | Stock Option (right to buy) | 15k | $4.82 | $72.3k | | 06/11/2014 |
| 05/21/2014 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Common Stock | 25k | $0.88 | $21.9k | | 05/21/2014 |
| 03/20/2013 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Common Stock | 15k | $3.00 | $45k | | 01/17/2012 |
| 01/01/2013 | OPTIMER PHARMACEUTICALS INC | OPTR | Grant | Common Stock | 7.5k | $0.00 | $0 | | 01/01/2013 |
| 05/31/2012 | OPTIMER PHARMACEUTICALS INC | OPTR | Grant | Common stock | 2.5k | $0.00 | $0 | | 05/31/2012 |
| 01/17/2012 | ASSEMBLY BIOSCIENCES, INC. | ASMB | Grant | Stock Options (Right to Buy) | 35k | $8.10 | $283.5k | | 01/17/2012 |
| 12/01/2010 | OPTIMER PHARMACEUTICALS INC | OPTR | Grant | Stock Option (Right to Buy) | 10k | $9.56 | $95.6k | | 12/01/2010 |