| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/30/2023 | Kodiak Sciences Inc. | KOD | Grant | Stock Option (Right to Buy) | 40k | $6.90 | $276k | | 06/30/2023 |
| 06/29/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Exercise | Restricted Share Units | 5k | $0.00 | $0 | | 06/29/2023 |
| 06/07/2023 | Protara Therapeutics, Inc. | PRTO | Grant | Stock Option (Right to Buy) | 10k | $2.85 | $28.5k | | 06/07/2023 |
| 06/06/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 26.2k | $15.19 | $398.5k | | 06/06/2023 |
| 06/06/2023 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Restricted Share Units | 4.4k | $0.00 | $0 | | 06/06/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 100 | $285.28 | $28.5k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 400 | $287.08 | $114.8k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 300 | $288.91 | $86.7k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 1.6k | $290.36 | $464.6k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 3.3k | $291.66 | $969.8k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 5.2k | $292.68 | $1.5M | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 3.5k | $293.54 | $1M | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 5.2k | $294.68 | $1.5M | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 2.3k | $295.45 | $686.9k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Sale | Common Stock | 500 | $296.68 | $148.3k | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Exercise | Stock Option (Right to buy) | 12.5k | $105.08 | $1.3M | | 01/17/2023 |
| 01/17/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Exercise | Stock Option (Right to Buy) | 10k | $100.45 | $1M | | 01/17/2023 |
| 06/30/2022 | Kodiak Sciences Inc. | KOD | Grant | Stock Option (Right to Buy) | 25k | $7.64 | $191k | | 06/30/2022 |
| 06/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 30k | $9.88 | $296.4k | | 06/29/2022 |
| 06/29/2022 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Restricted Share Units | 5k | $0.00 | $0 | | 06/29/2022 |
| 06/08/2022 | Protara Therapeutics, Inc. | PRTO | Grant | Stock Option (Right to Buy) | 10k | $3.50 | $35k | | 06/08/2022 |
| 07/15/2021 | CONSTELLATION PHARMACEUTICALS INC | CNST | Disposition | Stock Option (right to buy) | 13.2k | $33.57 | $442.2k | | 07/15/2021 |
| 07/15/2021 | CONSTELLATION PHARMACEUTICALS INC | CNST | Disposition | Stock Option (right to buy) | 26.3k | $30.29 | $797.9k | | 07/15/2021 |
| 06/30/2021 | Kodiak Sciences Inc. | KOD | Grant | Stock Option (Right to Buy) | 7.4k | $93.00 | $685.2k | | 06/30/2021 |
| 06/29/2021 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 33.2k | $14.33 | $476.3k | | 06/29/2021 |
| 06/17/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to buy) | 12.5k | $105.08 | $1.3M | | 06/17/2021 |
| 06/09/2021 | Protara Therapeutics, Inc. | PRTO | Grant | Stock Option (Right to Buy) | 10k | $10.51 | $105.1k | | 06/09/2021 |
| 06/02/2021 | CONSTELLATION PHARMACEUTICALS INC | CNST | Grant | Stock Option (right to buy) | 13.2k | $33.57 | $442.2k | | 06/02/2021 |
| 06/30/2020 | Kiniksa Pharmaceuticals, Ltd. | KNSA | Grant | Share Option | 18.8k | $25.48 | $478k | | 06/30/2020 |
| 06/30/2020 | Kodiak Sciences Inc. | KOD | Grant | Stock Option (Right to Buy) | 7.1k | $54.12 | $384.6k | | 06/30/2020 |
| 06/17/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | Grant | Stock Option (Right to buy) | 6k | $111.06 | $666.4k | | 06/17/2020 |
| 06/09/2020 | Protara Therapeutics, Inc. | PRTO | Grant | Stock Option (Right to Buy) | 9k | $35.00 | $315k | | 06/09/2020 |
| 06/08/2020 | Kodiak Sciences Inc. | KOD | Grant | Stock Option (Right to Buy) | 4.1k | $62.50 | $258.4k | | 06/08/2020 |
| 04/03/2020 | CONSTELLATION PHARMACEUTICALS INC | CNST | Grant | Stock Option (right to buy) | 26.3k | $30.29 | $797.9k | | 04/03/2020 |
| 03/20/2020 | Kodiak Sciences Inc. | KOD | Purchase | Common Stock | 250 | $43.37 | $10.8k | | 03/20/2020 |
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