Type	Name	Date
Underwriting agreement	Underwriting Agreement, among Xenon Pharmaceuticals Inc., Jefferies LLC and Stifel, Nicolaus & Company, Incorporated, as representatives of the several underwriters named therein	03/10/2021
Underwriting agreement	Underwriting Agreement, among Xenon Pharmaceuticals, Inc., Jefferies LLC and Stifel, Nicolaus & Company, Incorporated, as representatives of the several underwriters named therein	09/13/2018

Type	Name	Date
Employment agreement	Employment Agreement, by and between the Company and Ian Mortimer	01/14/2021
Employment agreement	Employment Agreement, by and between the Company and Simon Pimstone	01/14/2021
Employment agreement	Amended and Restated Employment Agreement, by and between the Company and Simon Pimstone	03/25/2019
Employment agreement	Amended and Restated Employment Agreement, by and between the Company and Ian Mortimer	03/25/2019
Employment agreement	Amended and Restated Employment Agreement, by and between the Company and Ernesto Aycardi	03/25/2019

Type	Name	Date
Acquisition / asset purchase agreement	Share Purchase Agreement, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc	01/12/2022
Acquisition / asset purchase agreement	Share Purchase Agreement, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc	09/08/2021
Exchange agreement	Exchange Agreement, by and among the Company and the shareholders listed in Schedule B thereto	03/28/2018

Type	Name	Date
Lease agreement	Lease Agreement, by and between the Company and Redstone Enterprises Ltd	12/01/2021