Type	Name	Date
Underwriting agreement	Underwriting Agreement, between Spero Therapeutics, Inc. and Cowen and Company, LLC and Evercore Group, L.L.C., as representatives of the several underwriters named therein	09/14/2020

Type	Name	Date
By-Laws	Amended and Restated Bylaws of Spero Therapeutics, Inc	11/06/2017

Type	Name	Date
Equity incentive plans	Spero Therapeutics, Inc. 2017 Stock Incentive Plan, as amended	10/10/2023
Equity incentive plans	Spero Therapeutics, Inc. 2017 Stock Incentive Plan, as amended	10/10/2023
Equity incentive plans	Spero Therapeutics, Inc. 2017 Stock Incentive Plan, as amended	09/19/2022
Equity incentive plans	Spero Therapeutics, Inc. 2017 Stock Incentive Plan, as amended	09/19/2022
Equity incentive plans	Spero Therapeutics, Inc. 2017 Stock Incentive Plan, as amended	08/18/2021