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DAFNA Capital Management LLC
> IBB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 0 | 13,013,400,000 | -225,500,000 | $126,960.00 |
| 03/31/2023 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 0 | 13,238,900,000 | -218,325,000 | $129,160.00 |
| 12/31/2022 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 0 | 13,457,225,000 | 13,445,237,000 | $131,290.00 |
| 09/30/2022 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 0 | 11,988,000 | -69,000 | $116.96 |
| 06/30/2022 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 0 | 12,057,000 | -1,299,000 | $117.63 |
| 03/31/2022 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 102,500 | 61,600 | 13,356,000 | 7,114,000 | $130.30 |
| 12/31/2021 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 40,900 | 0 | 6,242,000 | -371,000 | $152.62 |
| 09/30/2021 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 40,900 | 0 | 6,613,000 | -80,000 | $161.69 |
| 06/30/2021 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 40,900 | -6,500 | 6,693,000 | -488,000 | $163.64 |
| 12/31/2020 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 47,400 | -8,500 | 7,181,000 | -388,000 | $151.50 |
| 09/30/2020 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 55,900 | 1,000 | 7,569,000 | 65,000 | $135.40 |
| 06/30/2020 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 54,900 | -18,000 | 7,504,000 | -350,000 | $136.68 |
| 03/31/2020 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 72,900 | 8,000 | 7,854,000 | 33,000 | $107.74 |
| 12/31/2019 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 64,900 | 0 | 7,821,000 | 1,363,000 | $120.51 |
| 09/30/2019 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 64,900 | 3,500 | 6,458,000 | -241,000 | $99.51 |
| 06/30/2019 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 61,400 | 0 | 6,699,000 | -166,000 | $109.10 |
| 03/31/2019 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 61,400 | -3,500 | 6,865,000 | 607,000 | $111.81 |
| 12/31/2018 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 64,900 | 38,800 | 6,258,000 | 3,075,000 | $96.43 |
| 09/30/2018 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 26,100 | 0 | 3,183,000 | 317,000 | $121.95 |
| 06/30/2018 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 26,100 | 0 | 2,866,000 | 80,000 | $109.81 |
| 03/31/2018 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 26,100 | 0 | 2,786,000 | -1,000 | $106.74 |
| 12/31/2017 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 26,100 | 17,400 | 2,787,000 | -115,000 | $106.78 |
| 09/30/2017 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 8,700 | 0 | 2,902,000 | 204,000 | $333.56 |
| 06/30/2017 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 8,700 | 0 | 2,698,000 | 147,000 | $310.11 |
| 03/31/2017 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 8,700 | 0 | 2,551,000 | 242,000 | $293.22 |
| 12/31/2016 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 8,700 | 8,700 | 2,309,000 | 2,309,000 | $265.40 |
| 09/30/2016 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 0 | -6,000 | 0 | -1,544,000 | |
| 06/30/2016 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 6,000 | 6,000 | 1,544,000 | 1,544,000 | $257.33 |
| 03/31/2016 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 6,000 | 6,000 | 1,565,000 | 1,565,000 | $260.83 |
| 09/30/2007 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 0 | -24,500 | 0 | -1,905,000 | |
| 03/31/2007 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 0 | -24,500 | 0 | -1,905,000 | |
| 12/31/2006 | ISHARES NASDAQ BIOTECHNOLOGY INDEX FUND | IBB | 24,500 | 24,500 | 1,905,000 | 1,905,000 | $77.76 |
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