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FIRST TRUST ADVISORS LP
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Ultragenyx Pharmaceutical Inc. | RARE | 1,154,836 | -57,780 | 53,272,584,000 | 4,646,683,000 | $46,130.00 |
| 03/31/2023 | Ultragenyx Pharmaceutical Inc. | RARE | 1,212,616 | 528,272 | 48,625,901,000 | 48,597,562,000 | $40,100.00 |
| 09/30/2022 | Ultragenyx Pharmaceutical Inc. | RARE | 684,344 | 118,699 | 28,339,000 | -5,407,000 | $41.41 |
| 06/30/2022 | Ultragenyx Pharmaceutical Inc. | RARE | 565,645 | -158,113 | 33,746,000 | -18,813,000 | $59.66 |
| 03/31/2022 | Ultragenyx Pharmaceutical Inc. | RARE | 723,758 | -18,883 | 52,559,000 | -9,890,000 | $72.62 |
| 12/31/2021 | Ultragenyx Pharmaceutical Inc. | RARE | 742,641 | 25,533 | 62,449,000 | -2,227,000 | $84.09 |
| 09/30/2021 | Ultragenyx Pharmaceutical Inc. | RARE | 717,108 | 123,165 | 64,676,000 | 8,044,000 | $90.19 |
| 06/30/2021 | Ultragenyx Pharmaceutical Inc. | RARE | 593,943 | 35,364 | 56,632,000 | -6,968,000 | $95.35 |
| 03/31/2021 | Ultragenyx Pharmaceutical Inc. | RARE | 558,579 | -205,226 | 63,600,000 | -42,134,000 | $113.86 |
| 12/31/2020 | Ultragenyx Pharmaceutical Inc. | RARE | 763,805 | -173,709 | 105,734,000 | 28,680,000 | $138.43 |
| 09/30/2020 | Ultragenyx Pharmaceutical Inc. | RARE | 937,514 | -234,195 | 77,054,000 | -14,597,000 | $82.19 |
| 06/30/2020 | Ultragenyx Pharmaceutical Inc. | RARE | 1,171,709 | 225,205 | 91,651,000 | 49,598,000 | $78.22 |
| 03/31/2020 | Ultragenyx Pharmaceutical Inc. | RARE | 946,504 | -241,459 | 42,053,000 | -8,685,000 | $44.43 |
| 12/31/2019 | Ultragenyx Pharmaceutical Inc. | RARE | 1,187,963 | 188,797 | 50,738,000 | 7,994,000 | $42.71 |
| 09/30/2019 | Ultragenyx Pharmaceutical Inc. | RARE | 999,166 | -516,029 | 42,744,000 | -53,471,000 | $42.78 |
| 06/30/2019 | Ultragenyx Pharmaceutical Inc. | RARE | 1,515,195 | -343,857 | 96,215,000 | -32,729,000 | $63.50 |
| 03/31/2019 | Ultragenyx Pharmaceutical Inc. | RARE | 1,859,052 | 387,118 | 128,944,000 | 64,944,000 | $69.36 |
| 12/31/2018 | Ultragenyx Pharmaceutical Inc. | RARE | 1,471,934 | 208,468 | 64,000,000 | -32,453,000 | $43.48 |
| 09/30/2018 | Ultragenyx Pharmaceutical Inc. | RARE | 1,263,466 | 285,961 | 96,453,000 | 21,312,000 | $76.34 |
| 06/30/2018 | Ultragenyx Pharmaceutical Inc. | RARE | 977,505 | 16,713 | 75,141,000 | 26,150,000 | $76.87 |
| 03/31/2018 | Ultragenyx Pharmaceutical Inc. | RARE | 960,792 | 175,098 | 48,991,000 | 12,551,000 | $50.99 |
| 12/31/2017 | Ultragenyx Pharmaceutical Inc. | RARE | 785,694 | 259,816 | 36,440,000 | 8,432,000 | $46.38 |
| 09/30/2017 | Ultragenyx Pharmaceutical Inc. | RARE | 525,878 | 14,138 | 28,008,000 | -3,776,000 | $53.26 |
| 06/30/2017 | Ultragenyx Pharmaceutical Inc. | RARE | 511,740 | 118,073 | 31,784,000 | 5,101,000 | $62.11 |
| 03/31/2017 | Ultragenyx Pharmaceutical Inc. | RARE | 393,667 | -7,820 | 26,683,000 | -1,546,000 | $67.78 |
| 12/31/2016 | Ultragenyx Pharmaceutical Inc. | RARE | 401,487 | 401,487 | 28,229,000 | 28,229,000 | $70.31 |
| 06/30/2016 | Ultragenyx Pharmaceutical Inc. | RARE | 0 | -28,063 | 0 | -3,148,000 | |
| 03/31/2016 | Ultragenyx Pharmaceutical Inc. | RARE | 0 | -28,063 | 0 | -3,148,000 | |
| 12/31/2015 | Ultragenyx Pharmaceutical Inc. | RARE | 28,063 | 28,063 | 3,148,000 | 3,148,000 | $112.18 |
| 09/30/2015 | Ultragenyx Pharmaceutical Inc. | RARE | 27,916 | 27,916 | 2,689,000 | 2,689,000 | $96.32 |
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