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ACADIAN ASSET MANAGEMENT LLC
> APTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Aptinyx Inc. | APTX | 224,265 | -155,061 | 16,000 | -30,000 | $0.07 |
| 03/31/2023 | Aptinyx Inc. | APTX | 379,326 | 252,549 | 46,000 | 11,000 | $0.12 |
| 12/31/2022 | Aptinyx Inc. | APTX | 126,777 | 0 | 35,000 | -10,000 | $0.28 |
| 09/30/2022 | Aptinyx Inc. | APTX | 126,777 | 67,392 | 45,000 | 12,000 | $0.35 |
| 06/30/2022 | Aptinyx Inc. | APTX | 59,385 | 59,385 | 33,000 | 33,000 | $0.56 |
| 03/31/2021 | Aptinyx Inc. | APTX | 0 | -69,703 | 0 | -241,000 | |
| 12/31/2020 | Aptinyx Inc. | APTX | 69,703 | -156,276 | 241,000 | -524,000 | $3.46 |
| 09/30/2020 | Aptinyx Inc. | APTX | 225,979 | -25,609 | 765,000 | -284,000 | $3.39 |
| 06/30/2020 | Aptinyx Inc. | APTX | 251,588 | 54,008 | 1,049,000 | 622,000 | $4.17 |
| 03/31/2020 | Aptinyx Inc. | APTX | 197,580 | 84,981 | 427,000 | 42,000 | $2.16 |
| 12/31/2019 | Aptinyx Inc. | APTX | 112,599 | 4,838 | 385,000 | 9,000 | $3.42 |
| 09/30/2019 | Aptinyx Inc. | APTX | 107,761 | 49,428 | 376,000 | 181,000 | $3.49 |
| 06/30/2019 | Aptinyx Inc. | APTX | 58,333 | 58,333 | 195,000 | 195,000 | $3.34 |
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