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PRIMECAP MANAGEMENT CO
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,078,107 | -486,002 | 1,606,002,327,000 | -448,243,177,000 | $521,750.00 |
| 03/31/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,564,109 | -232,948 | 2,054,245,504,000 | 2,052,319,675,000 | $576,370.00 |
| 09/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,797,057 | -55,395 | 1,925,829,000 | -167,131,000 | $507.19 |
| 06/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,852,452 | -85,055 | 2,092,960,000 | -232,729,000 | $543.28 |
| 03/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,937,507 | -167,595 | 2,325,689,000 | -413,399,000 | $590.65 |
| 12/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,105,102 | -196,360 | 2,739,088,000 | 281,534,000 | $667.24 |
| 09/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,301,462 | -185,712 | 2,457,554,000 | 409,698,000 | $571.33 |
| 03/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,487,174 | 41,649 | 2,047,856,000 | -22,781,000 | $456.38 |
| 12/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,445,525 | -152,716 | 2,070,637,000 | 40,422,000 | $465.78 |
| 09/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,598,241 | -142,200 | 2,030,215,000 | 312,564,000 | $441.52 |
| 06/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,740,441 | -104,910 | 1,717,651,000 | 343,509,000 | $362.34 |
| 03/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,845,351 | 92,885 | 1,374,142,000 | -169,792,000 | $283.60 |
| 12/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,752,466 | -8,340 | 1,543,934,000 | 157,254,000 | $324.87 |
| 09/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,760,806 | -209,350 | 1,386,680,000 | -72,955,000 | $291.27 |
| 06/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,970,156 | -46,680 | 1,459,635,000 | 86,427,000 | $293.68 |
| 03/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,016,836 | -4,110 | 1,373,208,000 | 249,570,000 | $273.72 |
| 12/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,020,946 | 1,572 | 1,123,638,000 | -101,491,000 | $223.79 |
| 09/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,019,374 | -68,380 | 1,225,129,000 | 171,252,000 | $244.08 |
| 06/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,087,754 | -19,430 | 1,053,877,000 | -552,000 | $207.14 |
| 03/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,107,184 | -37,060 | 1,054,429,000 | 77,640,000 | $206.46 |
| 12/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,144,244 | -56,036 | 976,789,000 | -7,104,000 | $189.88 |
| 09/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,200,280 | -83,090 | 983,893,000 | 62,103,000 | $189.20 |
| 06/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,283,370 | 11,880 | 921,790,000 | 112,089,000 | $174.47 |
| 03/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,271,490 | -33,240 | 809,701,000 | 61,204,000 | $153.60 |
| 12/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,304,730 | 99,860 | 748,497,000 | -79,390,000 | $141.10 |
| 09/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,204,870 | -157,530 | 827,887,000 | 35,539,000 | $159.06 |
| 06/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,362,400 | 5,362,400 | 792,348,000 | 792,348,000 | $147.76 |
| 03/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,439,360 | 39,470 | 770,159,000 | 4,185,000 | $141.59 |
| 12/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,399,890 | 912,800 | 765,974,000 | 203,786,000 | $141.85 |
| 09/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,401,253 | 914,163 | 660,465,000 | 98,277,000 | $122.28 |
| 06/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,520,640 | 1,033,550 | 716,358,000 | 154,170,000 | $129.76 |
| 03/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 5,168,990 | 681,900 | 694,402,000 | 132,214,000 | $134.34 |
| 12/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,487,090 | 4,487,090 | 562,188,000 | 562,188,000 | $125.29 |
| 09/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 4,308,150 | 746,350 | 524,302,000 | 96,031,000 | $121.70 |
| 06/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 3,962,230 | 400,430 | 467,543,000 | 39,272,000 | $118.00 |
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