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RENAISSANCE GROUP LLC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 93,931 | -1,723 | 33,055,397,000 | 2,917,754,000 | $351,911.48 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 95,654 | 50 | 30,137,643,000 | 2,529,120,000 | $315,069.34 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 95,604 | -748 | 27,608,523,000 | 27,580,625,000 | $288,780.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 96,352 | -9,916 | 27,898,000 | -2,047,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 106,268 | -29,038 | 29,945,000 | -5,366,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 135,306 | 10,191 | 35,311,000 | 7,836,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 125,115 | 6,265 | 27,475,000 | 5,917,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 118,850 | 17,365 | 21,558,000 | 1,096,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 101,485 | 18,443 | 20,462,000 | 836,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 83,042 | 4,148 | 19,626,000 | -1,843,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 78,894 | -589 | 21,469,000 | -1,606,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 79,483 | 79,483 | 23,075,000 | 23,075,000 | $290.31 |
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