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GUGGENHEIM CAPITAL LLC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 158,732 | -4,115 | 55,859,378,000 | 4,551,174,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 162,847 | -6,112 | 51,308,204,000 | 2,516,224,000 | $315,070.00 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 168,959 | -6,140 | 48,791,980,000 | 48,741,281,000 | $288,780.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 175,099 | -20,047 | 50,699,000 | -4,291,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 195,146 | -25,465 | 54,990,000 | -2,582,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 220,611 | 8,939 | 57,572,000 | 11,089,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 211,672 | -4,580 | 46,483,000 | 2,879,000 | $219.60 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 216,252 | 12,343 | 43,604,000 | -214,000 | $201.64 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 203,909 | -5,881 | 43,818,000 | -5,765,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 209,790 | 17,699 | 49,583,000 | -2,690,000 | $236.35 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 192,091 | -3,079 | 52,273,000 | -4,387,000 | $272.13 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 195,170 | 3,640 | 56,660,000 | 11,085,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 191,530 | -21,965 | 45,575,000 | -1,169,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 213,495 | -20,187 | 46,744,000 | 7,154,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 233,682 | -2,694 | 39,590,000 | -3,757,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 236,376 | -10,327 | 43,347,000 | -2,033,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 246,703 | 12,245 | 45,380,000 | 6,528,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 234,458 | -24,893 | 38,852,000 | -11,135,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 259,351 | -3,346 | 49,987,000 | 5,339,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 262,697 | -473,152 | 44,648,000 | -75,280,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 735,849 | -68,978 | 119,928,000 | -683,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 804,827 | 376,093 | 120,611,000 | 55,427,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 428,734 | -68,817 | 65,184,000 | 1,065,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 497,551 | -72,719 | 64,119,000 | 1,763,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 570,270 | -44,889 | 62,356,000 | 17,036,000 | $109.34 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 615,159 | 114,038 | 45,320,000 | 1,617,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 501,121 | 501,121 | 43,703,000 | 43,703,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 503,070 | -2,246 | 43,274,000 | -20,310,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 517,101 | 11,785 | 41,105,000 | -22,479,000 | $79.49 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 505,316 | -7,417 | 63,584,000 | 10,187,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 512,733 | -92,952 | 53,397,000 | -18,057,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 634,716 | 29,031 | 78,376,000 | 6,922,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 605,685 | 30,190 | 71,454,000 | 39,813,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 515,533 | -59,962 | 61,245,000 | 29,604,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -575,495 | 0 | -31,641,000 | |
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