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FIRST QUADRANT LLC
> AMGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2022 | AMGEN INC | AMGN | 0 | -20,475 | 0 | -4,606,000 | |
| 12/31/2021 | AMGEN INC | AMGN | 20,475 | 0 | 4,606,000 | 252,000 | $224.96 |
| 09/30/2021 | AMGEN INC | AMGN | 20,475 | 0 | 4,354,000 | -637,000 | $212.65 |
| 06/30/2021 | AMGEN INC | AMGN | 20,475 | -3,352 | 4,991,000 | -487,000 | $243.76 |
| 12/31/2020 | AMGEN INC | AMGN | 23,827 | -2,859 | 5,478,000 | -1,305,000 | $229.91 |
| 09/30/2020 | AMGEN INC | AMGN | 26,686 | -3,037 | 6,783,000 | -227,000 | $254.18 |
| 06/30/2020 | AMGEN INC | AMGN | 29,723 | 3,037 | 7,010,000 | 1,600,000 | $235.84 |
| 03/31/2020 | AMGEN INC | AMGN | 26,686 | 0 | 5,410,000 | -1,023,000 | $202.73 |
| 12/31/2019 | AMGEN INC | AMGN | 26,686 | 0 | 6,433,000 | 1,269,000 | $241.06 |
| 09/30/2019 | AMGEN INC | AMGN | 26,686 | -42,041 | 5,164,000 | -7,501,000 | $193.51 |
| 06/30/2019 | AMGEN INC | AMGN | 68,727 | -1,026 | 12,665,000 | -587,000 | $184.28 |
| 03/31/2019 | AMGEN INC | AMGN | 69,753 | -2,048 | 13,252,000 | -726,000 | $189.98 |
| 12/31/2018 | AMGEN INC | AMGN | 71,801 | 700 | 13,978,000 | -761,000 | $194.68 |
| 09/30/2018 | AMGEN INC | AMGN | 71,101 | -49,255 | 14,739,000 | -7,478,000 | $207.30 |
| 06/30/2018 | AMGEN INC | AMGN | 120,356 | -38,318 | 22,217,000 | -4,834,000 | $184.59 |
| 03/31/2018 | AMGEN INC | AMGN | 158,674 | -155,391 | 27,051,000 | -27,565,000 | $170.48 |
| 12/31/2017 | AMGEN INC | AMGN | 314,065 | 154,499 | 54,616,000 | 24,865,000 | $173.90 |
| 09/30/2017 | AMGEN INC | AMGN | 159,566 | -168,957 | 29,751,000 | -26,831,000 | $186.45 |
| 06/30/2017 | AMGEN INC | AMGN | 328,523 | 146,396 | 56,582,000 | 26,700,000 | $172.23 |
| 03/31/2017 | AMGEN INC | AMGN | 182,127 | 182,127 | 29,882,000 | 29,882,000 | $164.07 |
| 06/30/2013 | AMGEN INC | AMGN | 0 | -296,662 | 0 | -30,411,000 | |
| 03/31/2013 | AMGEN INC | AMGN | 296,662 | -53,600 | 30,411,000 | 218,000 | $102.51 |
| 12/31/2012 | AMGEN INC | AMGN | 350,262 | 55,300 | 30,193,000 | 5,331,000 | $86.20 |
| 09/30/2012 | AMGEN INC | AMGN | 294,962 | 222,862 | 24,862,000 | 19,961,000 | $84.29 |
| 06/30/2012 | AMGEN INC | AMGN | 72,100 | 0 | 5,257,000 | 356,000 | $72.91 |
| 03/31/2012 | AMGEN INC | AMGN | 72,100 | 0 | 4,901,000 | 272,000 | $67.98 |
| 12/31/2011 | AMGEN INC | AMGN | 72,100 | -58,400 | 4,629,000 | -2,543,000 | $64.20 |
| 09/30/2011 | AMGEN INC | AMGN | 130,500 | -54,800 | 7,172,000 | -3,640,000 | $54.96 |
| 06/30/2011 | AMGEN INC | AMGN | 185,300 | 112,200 | 10,812,000 | 6,905,000 | $58.35 |
| 03/31/2011 | AMGEN INC | AMGN | 73,100 | -2,000 | 3,907,000 | -216,000 | $53.45 |
| 12/31/2010 | AMGEN INC | AMGN | 75,100 | -9,800 | 4,123,000 | -556,000 | $54.90 |
| 09/30/2010 | AMGEN INC | AMGN | 84,900 | -292,500 | 4,679,000 | -15,172,000 | $55.11 |
| 06/30/2010 | AMGEN INC | AMGN | 377,400 | -71,300 | 19,851,000 | -6,998,000 | $52.60 |
| 03/31/2010 | AMGEN INC | AMGN | 448,700 | 5,355 | 26,849,000 | 1,769,000 | $59.84 |
| 12/31/2009 | AMGEN INC | AMGN | 443,345 | 122,845 | 25,080,000 | 5,776,000 | $56.57 |
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