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BVF INC
> IONS
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | IONIS PHARMACEUTICALS INC | IONS | 2,846,015 | 1,724,206 | 116,771,995,000 | 74,401,269,000 | $41,030.00 |
| 12/31/2022 | IONIS PHARMACEUTICALS INC | IONS | 1,121,809 | -1,751,144 | 42,370,726,000 | 42,243,655,000 | $37,770.00 |
| 09/30/2022 | IONIS PHARMACEUTICALS INC | IONS | 2,872,953 | 1,596,379 | 127,071,000 | 79,812,000 | $44.23 |
| 06/30/2022 | IONIS PHARMACEUTICALS INC | IONS | 1,276,574 | 1,276,574 | 47,259,000 | 47,259,000 | $37.02 |
| 06/30/2021 | IONIS PHARMACEUTICALS INC | IONS | 0 | -1,364,461 | 0 | -77,147,000 | |
| 12/31/2020 | IONIS PHARMACEUTICALS INC | IONS | 1,364,461 | 629,406 | 77,147,000 | 42,269,000 | $56.54 |
| 09/30/2020 | IONIS PHARMACEUTICALS INC | IONS | 735,055 | -687,787 | 34,878,000 | -49,013,000 | $47.45 |
| 06/30/2020 | IONIS PHARMACEUTICALS INC | IONS | 1,422,842 | -521,675 | 83,891,000 | -8,046,000 | $58.96 |
| 03/31/2020 | IONIS PHARMACEUTICALS INC | IONS | 1,944,517 | -235,218 | 91,937,000 | -39,741,000 | $47.28 |
| 12/31/2019 | IONIS PHARMACEUTICALS INC | IONS | 2,179,735 | 1,244,187 | 131,678,000 | 75,629,000 | $60.41 |
| 09/30/2019 | IONIS PHARMACEUTICALS INC | IONS | 935,548 | 935,548 | 56,049,000 | 56,049,000 | $59.91 |
| 03/31/2019 | IONIS PHARMACEUTICALS INC | IONS | 0 | -9,399 | 0 | -508,000 | |
| 12/31/2018 | IONIS PHARMACEUTICALS INC | IONS | 9,399 | -510,601 | 508,000 | -26,314,000 | $54.05 |
| 09/30/2018 | IONIS PHARMACEUTICALS INC | IONS | 520,000 | -50,000 | 26,822,000 | 3,070,000 | $51.58 |
| 06/30/2018 | IONIS PHARMACEUTICALS INC | IONS | 570,000 | 570,000 | 23,752,000 | 23,752,000 | $41.67 |
| 09/30/2016 | IONIS PHARMACEUTICALS INC | IONS | 0 | -850,000 | 0 | -19,797,000 | |
| 06/30/2016 | IONIS PHARMACEUTICALS INC | IONS | 850,000 | 850,000 | 19,797,000 | 19,797,000 | $23.29 |
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