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MACQUARIE GROUP LTD
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,626,960 | 179,572 | 46,076,000,000 | 12,829,000,000 | $28,320.30 |
| 03/31/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,447,388 | 34,979 | 33,247,000,000 | -6,413,000,000 | $22,970.34 |
| 12/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,412,409 | 36,170 | 39,660,000,000 | 39,621,066,000 | $28,079.69 |
| 09/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,376,239 | 24,128 | 38,934,000 | 8,958,000 | $28.29 |
| 06/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,352,111 | -112,821 | 29,976,000 | -12,668,000 | $22.17 |
| 03/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,464,932 | 300,948 | 42,644,000 | 4,384,000 | $29.11 |
| 12/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,163,984 | 8,624 | 38,260,000 | -15,060,000 | $32.87 |
| 09/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,155,360 | 636 | 53,320,000 | -10,317,000 | $46.15 |
| 06/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,154,724 | 18,467 | 63,637,000 | 4,961,000 | $55.11 |
| 03/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,136,257 | 40,310 | 58,676,000 | 11,189,000 | $51.64 |
| 12/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,095,947 | -138,188 | 47,487,000 | 4,293,000 | $43.33 |
| 09/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,234,135 | 4,785 | 43,194,000 | -22,552,000 | $35.00 |
| 06/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,229,350 | 99,333 | 65,746,000 | 25,654,000 | $53.48 |
| 03/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,130,017 | 85,890 | 40,092,000 | -9,765,000 | $35.48 |
| 12/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,044,127 | 200,097 | 49,857,000 | 22,510,000 | $47.75 |
| 09/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 844,030 | 844,030 | 27,347,000 | 27,347,000 | $32.40 |
| 12/31/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 0 | -3,675 | 0 | -245,000 | |
| 09/30/2017 | AGIOS PHARMACEUTICALS, INC. | AGIO | 3,675 | 3,675 | 245,000 | 245,000 | $66.67 |
| 06/30/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 0 | -16,644 | 0 | -676,000 | |
| 03/31/2016 | AGIOS PHARMACEUTICALS, INC. | AGIO | 16,644 | -15,574 | 676,000 | -1,416,000 | $40.62 |
| 12/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 32,218 | 4,331 | 2,092,000 | 123,000 | $64.93 |
| 09/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 27,887 | 27,887 | 1,969,000 | 1,969,000 | $70.61 |
| 06/30/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 27,195 | 27,195 | 3,022,000 | 3,022,000 | $111.12 |
| 03/31/2015 | AGIOS PHARMACEUTICALS, INC. | AGIO | 22,095 | 22,095 | 2,084,000 | 2,084,000 | $94.32 |
| 12/31/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 12,844 | 12,844 | 1,439,000 | 1,439,000 | $112.04 |
| 06/30/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 0 | -2,411 | 0 | -94,000 | |
| 03/31/2014 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,411 | 2,411 | 94,000 | 94,000 | $38.99 |
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