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PERCEPTIVE ADVISORS LLC
> LYRA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Lyra Therapeutics, Inc. | LYRA | 12,757,562 | 3,610,832 | 52,433,579,000 | 23,712,847,000 | $4,110.00 |
| 12/31/2022 | Lyra Therapeutics, Inc. | LYRA | 9,146,730 | 0 | 28,720,732,000 | 28,674,907,000 | $3,140.00 |
| 09/30/2022 | Lyra Therapeutics, Inc. | LYRA | 9,146,730 | 0 | 45,825,000 | -5,854,000 | $5.01 |
| 06/30/2022 | Lyra Therapeutics, Inc. | LYRA | 9,146,730 | 5,924,170 | 51,679,000 | 38,724,000 | $5.65 |
| 03/31/2022 | Lyra Therapeutics, Inc. | LYRA | 3,222,560 | 0 | 12,955,000 | -1,095,000 | $4.02 |
| 12/31/2021 | Lyra Therapeutics, Inc. | LYRA | 3,222,560 | 0 | 14,050,000 | -15,353,000 | $4.36 |
| 09/30/2021 | Lyra Therapeutics, Inc. | LYRA | 3,222,560 | 0 | 29,403,000 | 3,526,000 | $9.12 |
| 06/30/2021 | Lyra Therapeutics, Inc. | LYRA | 3,222,560 | 0 | 25,877,000 | -11,472,000 | $8.03 |
| 03/31/2021 | Lyra Therapeutics, Inc. | LYRA | 3,222,560 | -1 | 37,349,000 | 612,000 | $11.59 |
| 12/31/2020 | Lyra Therapeutics, Inc. | LYRA | 3,222,561 | 0 | 36,737,000 | 709,000 | $11.40 |
| 09/30/2020 | Lyra Therapeutics, Inc. | LYRA | 3,222,561 | 0 | 36,028,000 | -515,000 | $11.18 |
| 06/30/2020 | Lyra Therapeutics, Inc. | LYRA | 3,222,561 | 3,222,561 | 36,543,000 | 36,543,000 | $11.34 |
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