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TWO SIGMA INVESTMENTS, LP
> ALEC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Alector, Inc. | ALEC | 287,716 | -78,589 | 1,729,173,000 | -538,255,000 | $6,010.00 |
| 03/31/2023 | Alector, Inc. | ALEC | 366,305 | 115,818 | 2,267,428,000 | -44,567,000 | $6,190.00 |
| 12/31/2022 | Alector, Inc. | ALEC | 250,487 | -10,739 | 2,311,995,000 | 2,309,341,000 | $9,230.00 |
| 06/30/2022 | Alector, Inc. | ALEC | 261,226 | -19,589 | 2,654,000 | -1,348,000 | $10.16 |
| 03/31/2022 | Alector, Inc. | ALEC | 280,815 | -67,072 | 4,002,000 | -3,182,000 | $14.25 |
| 12/31/2021 | Alector, Inc. | ALEC | 347,887 | 7,401 | 7,184,000 | -586,000 | $20.65 |
| 09/30/2021 | Alector, Inc. | ALEC | 340,486 | 340,486 | 7,770,000 | 7,770,000 | $22.82 |
| 03/31/2021 | Alector, Inc. | ALEC | 0 | -62,500 | 0 | -946,000 | |
| 12/31/2020 | Alector, Inc. | ALEC | 62,500 | -404,990 | 946,000 | -3,979,000 | $15.14 |
| 09/30/2020 | Alector, Inc. | ALEC | 467,490 | 284,586 | 4,925,000 | 455,000 | $10.53 |
| 06/30/2020 | Alector, Inc. | ALEC | 182,904 | 143,601 | 4,470,000 | 3,522,000 | $24.44 |
| 03/31/2020 | Alector, Inc. | ALEC | 39,303 | 39,303 | 948,000 | 948,000 | $24.12 |
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