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TWO SIGMA INVESTMENTS, LP
> AVTE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Aerovate Therapeutics, Inc. | AVTE | 30,011 | 18,502 | 514,689,000 | 282,552,000 | $17,150.01 |
| 03/31/2023 | Aerovate Therapeutics, Inc. | AVTE | 11,509 | -9,628 | 232,137,000 | -387,177,000 | $20,170.04 |
| 12/31/2022 | Aerovate Therapeutics, Inc. | AVTE | 21,137 | 21,137 | 619,314,000 | 619,314,000 | $29,300.00 |
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