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Marshall Wace North America L.P.
> UTHR
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2021 | UNITED THERAPEUTICS Corp | UTHR | 112,359 | 112,359 | 20,738,000 | 20,738,000 | $184.57 |
| 06/30/2021 | UNITED THERAPEUTICS Corp | UTHR | 0 | -272,286 | 0 | -45,545,000 | |
| 03/31/2021 | UNITED THERAPEUTICS Corp | UTHR | 272,286 | -38,023 | 45,545,000 | -1,557,000 | $167.27 |
| 12/31/2020 | UNITED THERAPEUTICS Corp | UTHR | 310,309 | -70,737 | 47,102,000 | 8,616,000 | $151.79 |
| 09/30/2020 | UNITED THERAPEUTICS Corp | UTHR | 381,046 | 62,710 | 38,486,000 | -33,000 | $101.00 |
| 06/30/2020 | UNITED THERAPEUTICS Corp | UTHR | 318,336 | 287,192 | 38,519,000 | 35,565,000 | $121.00 |
| 03/31/2020 | UNITED THERAPEUTICS Corp | UTHR | 31,144 | 31,144 | 2,954,000 | 2,954,000 | $94.85 |
| 09/30/2019 | UNITED THERAPEUTICS Corp | UTHR | 0 | -7,772 | 0 | -606,000 | |
| 06/30/2019 | UNITED THERAPEUTICS Corp | UTHR | 7,772 | 7,772 | 606,000 | 606,000 | $77.97 |
| 03/31/2019 | UNITED THERAPEUTICS Corp | UTHR | 0 | -12,327 | 0 | -1,343,000 | |
| 12/31/2018 | UNITED THERAPEUTICS Corp | UTHR | 12,327 | 12,327 | 1,343,000 | 1,343,000 | $108.95 |
| 09/30/2018 | UNITED THERAPEUTICS Corp | UTHR | 0 | -3,154 | 0 | -357,000 | |
| 06/30/2018 | UNITED THERAPEUTICS Corp | UTHR | 3,154 | 3,154 | 357,000 | 357,000 | $113.19 |
| 12/31/2017 | UNITED THERAPEUTICS Corp | UTHR | 0 | -31,964 | 0 | -3,740,000 | |
| 09/30/2017 | UNITED THERAPEUTICS Corp | UTHR | 31,964 | 31,964 | 3,740,000 | 3,740,000 | $117.01 |
| 06/30/2017 | UNITED THERAPEUTICS Corp | UTHR | 0 | -70,630 | 0 | -9,535,000 | |
| 03/31/2017 | UNITED THERAPEUTICS Corp | UTHR | 70,630 | 68,739 | 9,535,000 | 9,321,000 | $135.00 |
| 12/31/2016 | UNITED THERAPEUTICS Corp | UTHR | 0 | -1,891 | 0 | -214,000 | |
| 09/30/2016 | UNITED THERAPEUTICS Corp | UTHR | 0 | -1,891 | 0 | -214,000 | |
| 12/31/2013 | UNITED THERAPEUTICS Corp | UTHR | 1,891 | 1,891 | 214,000 | 214,000 | $113.17 |
| 06/30/2013 | UNITED THERAPEUTICS Corp | UTHR | 0 | -17,475 | 0 | -1,064,000 | |
| 03/31/2013 | UNITED THERAPEUTICS Corp | UTHR | 17,475 | 17,475 | 1,064,000 | 1,064,000 | $60.89 |
| 09/30/2012 | UNITED THERAPEUTICS Corp | UTHR | 0 | -11,821 | 0 | -584,000 | |
| 06/30/2012 | UNITED THERAPEUTICS Corp | UTHR | 11,821 | -64,030 | 584,000 | -2,991,000 | $49.40 |
| 03/31/2012 | UNITED THERAPEUTICS Corp | UTHR | 75,851 | 53,109 | 3,575,000 | 2,500,000 | $47.13 |
| 12/31/2011 | UNITED THERAPEUTICS Corp | UTHR | 22,742 | -8,608 | 1,075,000 | -100,000 | $47.27 |
| 09/30/2011 | UNITED THERAPEUTICS Corp | UTHR | 31,350 | -18,863 | 1,175,000 | -1,592,000 | $37.48 |
| 06/30/2011 | UNITED THERAPEUTICS Corp | UTHR | 50,213 | 36,019 | 2,767,000 | 1,816,000 | $55.11 |
| 03/31/2011 | UNITED THERAPEUTICS Corp | UTHR | 14,194 | 11,548 | 951,000 | 784,000 | $67.00 |
| 12/31/2010 | UNITED THERAPEUTICS Corp | UTHR | 2,646 | -14,121 | 167,000 | -651,000 | $63.11 |
| 06/30/2010 | UNITED THERAPEUTICS Corp | UTHR | 16,767 | 16,767 | 818,000 | 818,000 | $48.79 |
| 09/30/2009 | UNITED THERAPEUTICS Corp | UTHR | 0 | -4,147 | 0 | -346,000 | |
| 06/30/2009 | UNITED THERAPEUTICS Corp | UTHR | 4,147 | -6,082 | 346,000 | -330,000 | $83.43 |
| 03/31/2009 | UNITED THERAPEUTICS Corp | UTHR | 10,229 | 6,558 | 676,000 | 446,000 | $66.09 |
| 12/31/2008 | UNITED THERAPEUTICS Corp | UTHR | 3,671 | -36,116 | 230,000 | -3,659,000 | $62.65 |
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