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Artal Group S.A.
> KRYS
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Krystal Biotech, Inc. | KRYS | 349,669 | -62,413 | 41,051,000 | 8,060,000 | $117.40 |
| 03/31/2023 | Krystal Biotech, Inc. | KRYS | 412,082 | -87,918 | 32,991,000 | -1,859,000 | $80.06 |
| 09/30/2022 | Krystal Biotech, Inc. | KRYS | 500,000 | 0 | 34,850,000 | 2,020,000 | $69.70 |
| 06/30/2022 | Krystal Biotech, Inc. | KRYS | 500,000 | 0 | 32,830,000 | -440,000 | $65.66 |
| 03/31/2022 | Krystal Biotech, Inc. | KRYS | 500,000 | -200,000 | 33,270,000 | -15,695,000 | $66.54 |
| 12/31/2021 | Krystal Biotech, Inc. | KRYS | 700,000 | 200,000 | 48,965,000 | 22,860,000 | $69.95 |
| 09/30/2021 | Krystal Biotech, Inc. | KRYS | 500,000 | 0 | 26,105,000 | -7,895,000 | $52.21 |
| 06/30/2021 | Krystal Biotech, Inc. | KRYS | 500,000 | 262,500 | 34,000,000 | 19,750,000 | $68.00 |
| 12/31/2020 | Krystal Biotech, Inc. | KRYS | 237,500 | 0 | 14,250,000 | 4,026,000 | $60.00 |
| 09/30/2020 | Krystal Biotech, Inc. | KRYS | 237,500 | 37,500 | 10,224,000 | 1,940,000 | $43.05 |
| 06/30/2020 | Krystal Biotech, Inc. | KRYS | 200,000 | 100,000 | 8,284,000 | 3,960,000 | $41.42 |
| 03/31/2020 | Krystal Biotech, Inc. | KRYS | 100,000 | 20,000 | 4,324,000 | -106,000 | $43.24 |
| 12/31/2019 | Krystal Biotech, Inc. | KRYS | 80,000 | -70,000 | 4,430,000 | -779,000 | $55.38 |
| 09/30/2019 | Krystal Biotech, Inc. | KRYS | 150,000 | -150,000 | 5,209,000 | -6,872,000 | $34.73 |
| 06/30/2019 | Krystal Biotech, Inc. | KRYS | 300,000 | 0 | 12,081,000 | 2,211,000 | $40.27 |
| 03/31/2019 | Krystal Biotech, Inc. | KRYS | 300,000 | 25,000 | 9,870,000 | 4,155,000 | $32.90 |
| 12/31/2018 | Krystal Biotech, Inc. | KRYS | 275,000 | 125,000 | 5,715,000 | 3,078,000 | $20.78 |
| 09/30/2018 | Krystal Biotech, Inc. | KRYS | 150,000 | 0 | 2,637,000 | 406,000 | $17.58 |
| 06/30/2018 | Krystal Biotech, Inc. | KRYS | 150,000 | 0 | 2,231,000 | 717,000 | $14.87 |
| 03/31/2018 | Krystal Biotech, Inc. | KRYS | 150,000 | 0 | 1,514,000 | -64,000 | $10.09 |
| 12/31/2017 | Krystal Biotech, Inc. | KRYS | 150,000 | 50,000 | 1,578,000 | 581,000 | $10.52 |
| 09/30/2017 | Krystal Biotech, Inc. | KRYS | 100,000 | 100,000 | 997,000 | 997,000 | $9.97 |
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