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ORBIMED ADVISORS LLC
> BIIB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BIOGEN INC. | BIIB | 556,800 | 51,800 | 158,604,480,000 | 18,199,330,000 | $284,850.00 |
| 03/31/2023 | BIOGEN INC. | BIIB | 505,000 | 246,800 | 140,405,150,000 | 68,904,406,000 | $278,030.00 |
| 12/31/2022 | BIOGEN INC. | BIIB | 258,200 | 33,600 | 71,500,744,000 | 71,440,776,000 | $276,920.00 |
| 09/30/2022 | BIOGEN INC. | BIIB | 224,600 | 113,000 | 59,968,000 | 37,208,000 | $267.00 |
| 06/30/2022 | BIOGEN INC. | BIIB | 111,600 | -6,300 | 22,760,000 | -2,070,000 | $203.94 |
| 03/31/2022 | BIOGEN INC. | BIIB | 117,900 | -112,300 | 24,830,000 | -30,400,000 | $210.60 |
| 12/31/2021 | BIOGEN INC. | BIIB | 230,200 | 162,800 | 55,230,000 | 31,891,000 | $239.92 |
| 06/30/2021 | BIOGEN INC. | BIIB | 67,400 | -14,600 | 23,339,000 | 399,000 | $346.28 |
| 03/31/2021 | BIOGEN INC. | BIIB | 82,000 | -447,400 | 22,940,000 | -106,689,000 | $279.76 |
| 12/31/2020 | BIOGEN INC. | BIIB | 529,400 | -186,500 | 129,629,000 | -73,458,000 | $244.86 |
| 09/30/2020 | BIOGEN INC. | BIIB | 715,900 | 0 | 203,087,000 | 11,548,000 | $283.68 |
| 06/30/2020 | BIOGEN INC. | BIIB | 715,900 | 235,500 | 191,539,000 | 39,550,000 | $267.55 |
| 03/31/2020 | BIOGEN INC. | BIIB | 480,400 | 415,900 | 151,989,000 | 132,850,000 | $316.38 |
| 12/31/2019 | BIOGEN INC. | BIIB | 64,500 | 28,300 | 19,139,000 | 10,711,000 | $296.73 |
| 09/30/2019 | BIOGEN INC. | BIIB | 36,200 | -51,500 | 8,428,000 | -12,082,000 | $232.82 |
| 06/30/2019 | BIOGEN INC. | BIIB | 87,700 | 0 | 20,510,000 | -221,000 | $233.87 |
| 03/31/2019 | BIOGEN INC. | BIIB | 87,700 | -747,549 | 20,731,000 | -230,612,000 | $236.39 |
| 12/31/2018 | BIOGEN INC. | BIIB | 835,249 | -75,051 | 251,343,000 | -70,275,000 | $300.92 |
| 09/30/2018 | BIOGEN INC. | BIIB | 910,300 | -257,600 | 321,618,000 | -17,353,000 | $353.31 |
| 06/30/2018 | BIOGEN INC. | BIIB | 1,167,900 | 127,500 | 338,971,000 | 54,089,000 | $290.24 |
| 03/31/2018 | BIOGEN INC. | BIIB | 1,040,400 | -190,300 | 284,882,000 | -107,182,000 | $273.82 |
| 12/31/2017 | BIOGEN INC. | BIIB | 1,230,700 | -399,300 | 392,064,000 | -118,322,000 | $318.57 |
| 09/30/2017 | BIOGEN INC. | BIIB | 1,630,000 | 0 | 510,386,000 | 68,069,000 | $313.12 |
| 06/30/2017 | BIOGEN INC. | BIIB | 1,630,000 | 193,100 | 442,317,000 | 49,440,000 | $271.36 |
| 03/31/2017 | BIOGEN INC. | BIIB | 1,436,900 | 155,700 | 392,877,000 | 29,554,000 | $273.42 |
| 12/31/2016 | BIOGEN INC. | BIIB | 1,281,200 | -52,700 | 363,323,000 | -54,228,000 | $283.58 |
| 09/30/2016 | BIOGEN INC. | BIIB | 1,333,900 | -166,500 | 417,551,000 | 54,724,000 | $313.03 |
| 06/30/2016 | BIOGEN INC. | BIIB | 1,500,400 | 1,500,400 | 362,827,000 | 362,827,000 | $241.82 |
| 03/31/2016 | BIOGEN INC. | BIIB | 1,526,300 | 83,800 | 397,326,000 | -44,584,000 | $260.32 |
| 12/31/2015 | BIOGEN INC. | BIIB | 1,442,500 | 652,200 | 441,910,000 | 326,234,000 | $306.35 |
| 09/30/2015 | BIOGEN INC. | BIIB | 1,307,400 | 517,100 | 381,512,000 | 265,836,000 | $291.81 |
| 06/30/2015 | BIOGEN INC. | BIIB | 0 | -790,300 | 0 | -115,676,000 | |
| 03/31/2015 | BIOGEN INC. | BIIB | 1,206,800 | 416,500 | 509,559,000 | 393,883,000 | $422.24 |
| 12/31/2014 | BIOGEN INC. | BIIB | 1,494,700 | 704,400 | 507,376,000 | 391,700,000 | $339.45 |
| 09/30/2014 | BIOGEN INC. | BIIB | 1,190,100 | 399,800 | 393,697,000 | 278,021,000 | $330.81 |
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