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Pictet & Cie (Europe) SA
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,164 | -1,159 | 409,623,000 | -322,285,000 | $351,909.79 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,323 | 442 | 731,908,000 | 188,713,000 | $315,070.17 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,881 | -726 | 543,195,000 | 542,440,169 | $288,779.90 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,607 | -599 | 754,831 | -148,169 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,206 | -1,732 | 903,000 | -386,000 | $281.66 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,938 | -13,304 | 1,289,000 | -2,717,000 | $261.04 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 18,242 | -555 | 4,006,000 | 596,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 18,797 | -34,154 | 3,410,000 | -7,267,000 | $181.41 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 52,951 | 36,560 | 10,677,000 | 7,155,000 | $201.64 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 16,391 | -52,409 | 3,522,000 | -12,738,000 | $214.87 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 68,800 | 18,641 | 16,260,000 | 2,611,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 50,159 | 50,159 | 13,649,000 | 13,649,000 | $272.11 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -4,200 | 0 | -696,000 | |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,200 | 4,200 | 696,000 | 696,000 | $165.71 |
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