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VANGUARD GROUP INC
> BPMC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Blueprint Medicines Corp | BPMC | 5,929,427 | 268,324 | 374,739,786,000 | 374,366,777,000 | $63,200.00 |
| 09/30/2022 | Blueprint Medicines Corp | BPMC | 5,661,103 | 44,292 | 373,009,000 | 89,303,000 | $65.89 |
| 06/30/2022 | Blueprint Medicines Corp | BPMC | 5,616,811 | 91,751 | 283,706,000 | -69,235,000 | $50.51 |
| 03/31/2022 | Blueprint Medicines Corp | BPMC | 5,525,060 | -8,711 | 352,941,000 | -239,781,000 | $63.88 |
| 12/31/2021 | Blueprint Medicines Corp | BPMC | 5,533,771 | -49,361 | 592,722,000 | 18,721,000 | $107.11 |
| 09/30/2021 | Blueprint Medicines Corp | BPMC | 5,583,132 | 17,589 | 574,001,000 | 84,457,000 | $102.81 |
| 06/30/2021 | Blueprint Medicines Corp | BPMC | 5,565,543 | 379,031 | 489,544,000 | -92,123,000 | $87.96 |
| 02/10/2021 | Blueprint Medicines Corp | BPMC | 5,186,512 | 0 | 515,435,563 | -66,231,437 | $99.38 |
| 12/31/2020 | Blueprint Medicines Corp | BPMC | 5,186,512 | 391,732 | 581,667,000 | 137,191,000 | $112.15 |
| 09/30/2020 | Blueprint Medicines Corp | BPMC | 4,794,780 | -134,430 | 444,476,000 | 59,997,000 | $92.70 |
| 06/30/2020 | Blueprint Medicines Corp | BPMC | 4,929,210 | 52,550 | 384,479,000 | 99,293,000 | $78.00 |
| 03/31/2020 | Blueprint Medicines Corp | BPMC | 4,876,660 | 508,676 | 285,186,000 | -64,733,000 | $58.48 |
| 02/12/2020 | Blueprint Medicines Corp | BPMC | 4,367,984 | 0 | 282,783,284 | -67,135,716 | $64.74 |
| 12/31/2019 | Blueprint Medicines Corp | BPMC | 4,367,984 | 26,649 | 349,919,000 | 30,961,000 | $80.11 |
| 09/30/2019 | Blueprint Medicines Corp | BPMC | 4,341,335 | 59,973 | 318,958,000 | -84,903,000 | $73.47 |
| 06/30/2019 | Blueprint Medicines Corp | BPMC | 4,281,362 | 321,857 | 403,861,000 | 86,903,000 | $94.33 |
| 03/31/2019 | Blueprint Medicines Corp | BPMC | 3,959,505 | 141,543 | 316,958,000 | 111,132,000 | $80.05 |
| 02/11/2019 | Blueprint Medicines Corp | BPMC | 3,817,962 | 0 | 276,916,784 | 71,090,784 | $72.53 |
| 12/31/2018 | Blueprint Medicines Corp | BPMC | 3,817,962 | 82,572 | 205,826,000 | -85,758,000 | $53.91 |
| 09/30/2018 | Blueprint Medicines Corp | BPMC | 3,735,390 | 111,972 | 291,584,000 | 61,569,000 | $78.06 |
| 06/30/2018 | Blueprint Medicines Corp | BPMC | 3,623,418 | 241,363 | 230,015,000 | -80,119,000 | $63.48 |
| 03/31/2018 | Blueprint Medicines Corp | BPMC | 3,382,055 | 65,127 | 310,134,000 | 60,005,000 | $91.70 |
| 12/31/2017 | Blueprint Medicines Corp | BPMC | 3,316,928 | 1,382,699 | 250,129,000 | 115,371,000 | $75.41 |
| 09/30/2017 | Blueprint Medicines Corp | BPMC | 1,934,229 | 518,266 | 134,758,000 | 134,686,254 | $69.67 |
| 06/30/2017 | Blueprint Medicines Corp | BPMC | 1,415,963 | 195,517 | 71,746 | -48,734,254 | $0.05 |
| 03/31/2017 | Blueprint Medicines Corp | BPMC | 1,220,446 | 313,181 | 48,806,000 | 23,358,000 | $39.99 |
| 12/31/2016 | Blueprint Medicines Corp | BPMC | 907,265 | 194,790 | 25,448,000 | 4,287,000 | $28.05 |
| 09/30/2016 | Blueprint Medicines Corp | BPMC | 712,475 | 712,475 | 21,161,000 | 21,161,000 | $29.70 |
| 06/30/2016 | Blueprint Medicines Corp | BPMC | 566,995 | 39,253 | 11,481,000 | 1,955,000 | $20.25 |
| 03/31/2016 | Blueprint Medicines Corp | BPMC | 527,742 | 312,166 | 9,526,000 | 4,926,000 | $18.05 |
| 12/31/2015 | Blueprint Medicines Corp | BPMC | 504,456 | 288,880 | 13,287,000 | 8,687,000 | $26.34 |
| 09/30/2015 | Blueprint Medicines Corp | BPMC | 4,550,814 | 4,365,943 | 172,509,000 | 167,612,000 | $37.91 |
| 06/30/2015 | Blueprint Medicines Corp | BPMC | 184,871 | 184,871 | 4,897,000 | 4,897,000 | $26.49 |
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