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GREAT POINT PARTNERS LLC
> XENE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Xenon Pharmaceuticals Inc. | XENE | 530,000 | -320,000 | 20,405,000,000 | -13,110,500,000 | $38,500.00 |
| 12/31/2022 | Xenon Pharmaceuticals Inc. | XENE | 850,000 | 0 | 33,515,500,000 | 33,484,815,000 | $39,430.00 |
| 09/30/2022 | Xenon Pharmaceuticals Inc. | XENE | 850,000 | -254,334 | 30,685,000 | -2,909,000 | $36.10 |
| 06/30/2022 | Xenon Pharmaceuticals Inc. | XENE | 1,104,334 | 184,334 | 33,594,000 | 5,470,000 | $30.42 |
| 03/31/2022 | Xenon Pharmaceuticals Inc. | XENE | 920,000 | -30,000 | 28,124,000 | -1,554,000 | $30.57 |
| 12/31/2021 | Xenon Pharmaceuticals Inc. | XENE | 950,000 | 250,000 | 29,678,000 | 18,982,000 | $31.24 |
| 09/30/2021 | Xenon Pharmaceuticals Inc. | XENE | 700,000 | 700,000 | 10,696,000 | 10,696,000 | $15.28 |
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