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STATE STREET CORP
> MDGL
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 543,759 | -717,234 | 125,608,329,000 | -240,394,889,000 | $231,000.00 |
| 12/31/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 1,260,993 | 294,352 | 366,003,218,000 | 365,940,396,000 | $290,250.00 |
| 09/30/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 966,641 | 141,334 | 62,822,000 | 3,747,000 | $64.99 |
| 06/30/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 825,307 | 59,428 | 59,075,000 | -16,073,000 | $71.58 |
| 03/31/2022 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 765,879 | 167,131 | 75,148,000 | 24,410,000 | $98.12 |
| 12/31/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 598,748 | -159,867 | 50,738,000 | -9,792,000 | $84.74 |
| 09/30/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 758,615 | 136,153 | 60,530,000 | -104,000 | $79.79 |
| 06/30/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 622,462 | 36,712 | 60,634,000 | -7,881,000 | $97.41 |
| 03/31/2021 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 585,750 | -57,665 | 68,515,000 | -3,013,000 | $116.97 |
| 12/31/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 643,415 | 212,171 | 71,528,000 | 20,326,000 | $111.17 |
| 09/30/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 431,244 | -173,991 | 51,202,000 | -17,341,000 | $118.73 |
| 06/30/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 605,235 | 128,455 | 68,543,000 | 36,713,000 | $113.25 |
| 03/31/2020 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 476,780 | 18,402 | 31,830,000 | -9,933,000 | $66.76 |
| 12/31/2019 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 458,378 | -43,887 | 41,763,000 | -1,542,000 | $91.11 |
| 09/30/2019 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 502,265 | -115,481 | 43,305,000 | -21,441,000 | $86.22 |
| 06/30/2019 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 617,746 | 51,384 | 64,746,000 | -6,197,000 | $104.81 |
| 03/31/2019 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 566,362 | -34,065 | 70,943,000 | 3,263,000 | $125.26 |
| 12/31/2018 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 600,427 | 172,158 | 67,680,000 | -24,024,000 | $112.72 |
| 09/30/2018 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 428,269 | 85,763 | 91,704,000 | -4,096,000 | $214.13 |
| 06/30/2018 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 342,506 | 272,753 | 95,800,000 | 89,398,000 | $279.70 |
| 12/31/2017 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 69,753 | 24,933 | 6,402,000 | 4,390,000 | $91.78 |
| 09/30/2017 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 44,820 | 11,650 | 2,012,000 | 1,473,000 | $44.89 |
| 06/30/2017 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 33,170 | 33,170 | 539,000 | 539,000 | $16.25 |
| 09/30/2016 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 0 | -79,573 | 0 | -21,000 | |
| 06/30/2016 | MADRIGAL PHARMACEUTICALS, INC. | MDGL | 79,573 | 79,573 | 21,000 | 21,000 | $0.26 |
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