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VIRGINIA RETIREMENT SYSTEMS ET AL
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 297,900 | 3,900 | 104,833,989,000 | 12,203,409,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 294,000 | 23,800 | 92,630,580,000 | 14,602,224,000 | $315,070.00 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 270,200 | -14,600 | 78,028,356,000 | 77,954,032,000 | $288,780.00 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 284,800 | -16,100 | 74,324,000 | 8,246,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 300,900 | -5,800 | 66,078,000 | 10,446,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 306,700 | 19,900 | 55,632,000 | -2,195,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 286,800 | 167,600 | 57,827,000 | 29,655,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 119,200 | 47,400 | 28,172,000 | 8,634,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 71,800 | -1,800 | 19,538,000 | -1,829,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 73,600 | -100 | 21,367,000 | 3,830,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 73,700 | 5,400 | 17,537,000 | 2,583,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 68,300 | 31,200 | 14,954,000 | 8,669,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 37,100 | 600 | 6,285,000 | -408,000 | $169.41 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 36,500 | 36,500 | 6,693,000 | 6,693,000 | $183.37 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -3,500 | 0 | -675,000 | |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,500 | 0 | 675,000 | 80,000 | $192.86 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,500 | 3,500 | 595,000 | 595,000 | $170.00 |
| 09/30/2012 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -75,669 | 0 | -4,231,000 | |
| 06/30/2012 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 75,669 | 75,669 | 4,231,000 | 4,231,000 | $55.91 |
| 03/31/2012 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -81,507 | 0 | -2,707,000 | |
| 12/31/2011 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 81,507 | 81,507 | 2,707,000 | 2,707,000 | $33.21 |
| 09/30/2011 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -4,112 | 0 | -214,000 | |
| 06/30/2011 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,112 | 4,112 | 214,000 | 214,000 | $52.04 |
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