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ADAGE CAPITAL PARTNERS GP, L.L.C.
> PTGX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Protagonist Therapeutics, Inc | PTGX | 1,292,711 | -1,265,289 | 35,704,678,000 | -23,129,322,000 | $27,620.00 |
| 03/31/2023 | Protagonist Therapeutics, Inc | PTGX | 2,558,000 | 1,684,955 | 58,834,000,000 | 58,826,640,000 | $23,000.00 |
| 09/30/2022 | Protagonist Therapeutics, Inc | PTGX | 873,045 | -127,000 | 7,360,000 | -550,000 | $8.43 |
| 06/30/2022 | Protagonist Therapeutics, Inc | PTGX | 1,000,045 | 400,000 | 7,910,000 | -6,299,000 | $7.91 |
| 03/31/2022 | Protagonist Therapeutics, Inc | PTGX | 600,045 | 150,000 | 14,209,000 | -1,183,000 | $23.68 |
| 12/31/2021 | Protagonist Therapeutics, Inc | PTGX | 450,045 | 150,000 | 15,392,000 | 10,075,000 | $34.20 |
| 09/30/2021 | Protagonist Therapeutics, Inc | PTGX | 300,045 | -250,000 | 5,317,000 | -19,369,000 | $17.72 |
| 06/30/2021 | Protagonist Therapeutics, Inc | PTGX | 550,045 | -50,000 | 24,686,000 | 9,145,000 | $44.88 |
| 03/31/2021 | Protagonist Therapeutics, Inc | PTGX | 600,045 | -550,000 | 15,541,000 | -7,644,000 | $25.90 |
| 12/31/2020 | Protagonist Therapeutics, Inc | PTGX | 1,150,045 | -1,370,555 | 23,185,000 | -26,093,000 | $20.16 |
| 09/30/2020 | Protagonist Therapeutics, Inc | PTGX | 2,520,600 | 320,600 | 49,278,000 | 10,426,000 | $19.55 |
| 06/30/2020 | Protagonist Therapeutics, Inc | PTGX | 2,200,000 | 2,200,000 | 38,852,000 | 38,852,000 | $17.66 |
| 09/30/2018 | Protagonist Therapeutics, Inc | PTGX | 0 | -500,000 | 0 | -3,360,000 | |
| 06/30/2018 | Protagonist Therapeutics, Inc | PTGX | 500,000 | -500,000 | 3,360,000 | -5,230,000 | $6.72 |
| 03/31/2018 | Protagonist Therapeutics, Inc | PTGX | 1,000,000 | -1,056,076 | 8,590,000 | -34,176,000 | $8.59 |
| 12/31/2017 | Protagonist Therapeutics, Inc | PTGX | 2,056,076 | 0 | 42,766,000 | 6,435,000 | $20.80 |
| 09/30/2017 | Protagonist Therapeutics, Inc | PTGX | 2,056,076 | 0 | 36,331,000 | 13,077,000 | $17.67 |
| 06/30/2017 | Protagonist Therapeutics, Inc | PTGX | 2,056,076 | 400,000 | 23,254,000 | 2,040,000 | $11.31 |
| 05/30/2017 | Protagonist Therapeutics, Inc | PTGX | 2,056,076 | 400,000 | 24,302,818 | 3,088,818 | $11.82 |
| 03/31/2017 | Protagonist Therapeutics, Inc | PTGX | 1,656,076 | 125,000 | 21,214,000 | -12,454,000 | $12.81 |
| 12/31/2016 | Protagonist Therapeutics, Inc | PTGX | 1,531,076 | -50,000 | 33,668,000 | 260,000 | $21.99 |
| 09/30/2016 | Protagonist Therapeutics, Inc | PTGX | 1,581,076 | 1,581,076 | 33,408,000 | 33,408,000 | $21.13 |
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