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TIAA CREF INVESTMENT MANAGEMENT LLC
> SNNA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2019 | Sienna Biopharmaceuticals, Inc. | SNNA | 30,905 | 1,741 | 72,000 | 4,000 | $2.33 |
| 12/31/2018 | Sienna Biopharmaceuticals, Inc. | SNNA | 29,164 | -624 | 68,000 | -373,000 | $2.33 |
| 09/30/2018 | Sienna Biopharmaceuticals, Inc. | SNNA | 29,788 | -4,242 | 441,000 | -76,000 | $14.80 |
| 06/30/2018 | Sienna Biopharmaceuticals, Inc. | SNNA | 34,030 | 34,030 | 517,000 | 517,000 | $15.19 |
| 03/31/2018 | Sienna Biopharmaceuticals, Inc. | SNNA | 0 | -7,433 | 0 | -135,000 | |
| 12/31/2017 | Sienna Biopharmaceuticals, Inc. | SNNA | 7,433 | -813 | 135,000 | -48,000 | $18.16 |
| 09/30/2017 | Sienna Biopharmaceuticals, Inc. | SNNA | 8,246 | 8,246 | 183,000 | 183,000 | $22.19 |
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