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MILLENNIUM MANAGEMENT LLC
> ALPN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 116,175 | 116,175 | 1,194,279,000 | 1,194,279,000 | $10,280.00 |
| 06/30/2021 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 0 | -96,017 | 0 | -1,018,000 | |
| 03/31/2021 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 96,017 | 50,246 | 1,018,000 | 441,000 | $10.60 |
| 12/31/2020 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 45,771 | 45,771 | 577,000 | 577,000 | $12.61 |
| 12/31/2018 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 0 | -10,694 | 0 | -68,000 | |
| 09/30/2018 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 10,694 | 10,694 | 68,000 | 68,000 | $6.36 |
| 06/30/2018 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 0 | -13,705 | 0 | -110,000 | |
| 03/31/2018 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 13,705 | -4,567 | 110,000 | -95,000 | $8.03 |
| 12/31/2017 | ALPINE IMMUNE SCIENCES, INC. | ALPN | 18,272 | 18,272 | 205,000 | 205,000 | $11.22 |
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